Evidence map›Paper›PMID 32430545›Full record

ArticleDer Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen2021

[Percutaneous liver biopsy before organ removal-Impact on organ allocation and costs in liver transplantation].

Christian Beltzer, Markus Quante, Myriam Rheinberger, Hideo Andreas Baba, Fuat Saner, Falko Fend, Thomas Biet, Alfred Königsrainer, Silvio Nadalin

Open access · hybridAbstract read
In one paragraph

Article in Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Christian BeltzerKlinik für Allgemeine, Viszeral- und Transplantationschirurgie, Universitätsklinikum Tübingen, Tübingen, Deutschland.
Markus QuanteKlinik für Allgemeine, Viszeral- und Transplantationschirurgie, Universitätsklinikum Tübingen, Tübingen, Deutschland.
Myriam RheinbergerKlinik für Allgemeine, Viszeral- und Transplantationschirurgie, Universitätsklinikum Tübingen, Tübingen, Deutschland.
Hideo Andreas BabaInstitut für Pathologie, Universitätsklinikum Essen, Essen, Deutschland.
Fuat SanerKlinik für Allgemein‑, Viszeral- und Transplantationschirurgie, Universitätsklinikum Essen, Essen, Deutschland.
Falko FendInstitut für Pathologie und Neuropathologie, Universitätsklinikum Tübingen, Tübingen, Deutschland.
Thomas BietDeutsche Stiftung Organtransplantation, Frankfurt am Main, Deutschland.
Alfred KönigsrainerKlinik für Allgemeine, Viszeral- und Transplantationschirurgie, Universitätsklinikum Tübingen, Tübingen, Deutschland.
Silvio NadalinKlinik für Allgemeine, Viszeral- und Transplantationschirurgie, Universitätsklinikum Tübingen, Tübingen, Deutschland. silvio.nadalin@med.uni-tuebingen.de.
Universitätsklinikum Tübingen · DEEssen University Hospital · DEGerman Organ Transplantation Foundation · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe value and safety of percutaneous liver biopsy (PLB) in brain-dead donors before organ removal and its impact on organ allocation and costs of liver transplantation (LT) in the Eurotransplant (ET) region is still a matter of ongoing debate. MATERIAL AND

methodsA PLB was performed in 36 brain-dead organ donors. The complication rate, ultrasonography findings, macroscopic evaluation and histological results of PLB and donor characteristics were analyzed. Additionally, a nationwide survey was conducted among 11 liver transplantation experts. The need for PLB and its impact on the liver allocation process were evaluated. Possible cost savings were calculated for different scenarios based on cost data provided by the German Organ Transplantation Foundation.

resultsNo complications of PLB were observed. The survey revealed that the PLB has a substantial impact on the allocation of donor organs, especially in organs fulfilling extended donor criteria (EDC). The cost calculation revealed an enormous potential for cost savings due to an optimized organ allocation process and avoidance of futile organ procurement.

conclusionThe PLB is a safe procedure and has tremendous potential for the optimization of the organ allocation process before organ procurement by reducing the cold ischemia time, avoiding unnecessarily discarding donor organs and saving costs. These data emphasize the clinical relevance and impact of PLB on the organ allocation process.

Indexed as

Liver TransplantationTissue and Organ ProcurementBiopsyHumansLiverTissue DonorsCold ischemia timeDonor evaluationExtended donor criteriaLiver steatosis

Identifiers

PMID32430545
PMCPMC7820082
OpenAlexW3026175988

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.