Evidence map›Paper›PMID 32430394›Full record

ArticleMolecular & cellular proteomics : MCP2020

Dynamic Transcriptomic and Phosphoproteomic Analysis During Cell Wall Stress in

Cynthia Chelius, Walker Huso, Samantha Reese, Alexander Doan, Stephen Lincoln, Kelsi Lawson, Bao Tran, Raj Purohit, Trevor Glaros, Ranjan Srivastava and 2 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular & cellular proteomics : MCP, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Loss of theMicrobiology spectrum · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Cynthia CheliusDepartment of Chemical, Biochemical, and Environmental Engineering, University of Maryland Baltimore County, Baltimore, Maryland, USA.
Walker HusoDepartment of Chemical, Biochemical, and Environmental Engineering, University of Maryland Baltimore County, Baltimore, Maryland, USA.
Samantha ReeseCenter for Plant Science Innovation and Department of Plant Pathology, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.
Alexander DoanDepartment of Chemical, Biochemical, and Environmental Engineering, University of Maryland Baltimore County, Baltimore, Maryland, USA.
Stephen LincolnDepartment of Chemical and Biomolecular Engineering, University of Connecticut, Storrs, Connecticut, USA.
Kelsi LawsonDepartment of Chemical, Biochemical, and Environmental Engineering, University of Maryland Baltimore County, Baltimore, Maryland, USA.
Bao TranBioScience Mass Spectrometry Facility, The U.S. Army CCDC Chemical Biological Center, BioSciences Division, Aberdeen Proving Ground, Maryland, USA.
Raj PurohitDepartment of Chemical, Biochemical, and Environmental Engineering, University of Maryland Baltimore County, Baltimore, Maryland, USA.
Trevor GlarosBioSciences Division, B11 Bioenergy and Biome Sciences, Los Alamos National Laboratory, Los Alamos, New Mexico, USA.
Ranjan SrivastavaDepartment of Chemical and Biomolecular Engineering, University of Connecticut, Storrs, Connecticut, USA.
Steven D HarrisDepartment of Biological Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Mark R MartenDepartment of Chemical, Biochemical, and Environmental Engineering, University of Maryland Baltimore County, Baltimore, Maryland, USA. Electronic address: marten@umbc.edu.
University of Maryland, Baltimore County · USUniversity of Connecticut · USLos Alamos National Laboratory · USUnited States Army · USUniversity of Manitoba · CAUniversity of Nebraska–Lincoln · US

Funding

UNMC Structural Biology CoreP20GM103427 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI PAUL L SORGEN · 2012 to 2026
$59.2M
UNMC/EPPLEY CANCER CENTER SUPPORT GRANTP30CA036727 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Joann B. Sweasy · 1985 to 2026
$55.0M
UNMC Histology/Imaging and Creighton University Imaging Core FacilityP30GM110768 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI WALSH, EDWARD J · 2014 to 2018
$5.1M
NCI NIH HHS P30 CA036727NIGMS NIH HHS P20 GM103427NIGMS NIH HHS P30 GM110768
6 · The paper itself

Abstract

The fungal cell-wall integrity signaling (CWIS) pathway regulates cellular response to environmental stress to enable wall repair and resumption of normal growth. This complex, interconnected, pathway has been only partially characterized in filamentous fungi. To better understand the dynamic cellular response to wall perturbation, a β-glucan synthase inhibitor (micafungin) was added to a growing

Indexed as

ProteomicsAmino Acid SequenceAspergillus nidulansCell WallFungal ProteinsGene Expression Regulation, FungalMicafunginModels, BiologicalMutationPhosphoproteinsPhosphorylationProtein KinasesReproducibility of ResultsRNA-SeqStress, PhysiologicalTranscriptomeFungal ProteinsMicafunginPhosphoproteinsProtein Kinasescell wall signalingcell wall strengthfilamentous fungigene expressionmolecular dynamicspathway analysisphosphoproteomeSignaling moleculestranscriptomics

Identifiers

PMID32430394
PMCPMC8014999
OpenAlexW3028228569

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.