Evidence map›Paper›PMID 32430319›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Light-controlled twister ribozyme with single-molecule detection resolves RNA function in time and space.

Arthur Korman, Huabing Sun, Boyang Hua, Haozhe Yang, Joseph N Capilato, Rakesh Paul, Subrata Panja, Taekjip Ha, Marc M Greenberg, Sarah A Woodson

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Review
  3. RNAMolecular therapy. Nucleic acids · 2025
    Article
  4. Article
  5. Article
  6. Influence of MgACS omega · 2023
    Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Conditionally Activated ("Caged") Oligonucleotides.Molecules (Basel, Switzerland) · 2021
    Review
  15. Article
  16. Contributions and competition of MgRNA (New York, N.Y.) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Arthur KormanCell, Molecular, Developmental Biology and Biophysics Program, Johns Hopkins University, Baltimore, MD 21218.ORCID 0000-0003-4779-1041
Huabing SunDepartment of Chemistry, Johns Hopkins University, Baltimore, MD 21218.ORCID 0000-0002-5924-9738
Boyang HuaDepartment of Biophysics and Biochemistry, Johns Hopkins University, Baltimore, MD 21205-2185.
Haozhe YangDepartment of Chemistry, Johns Hopkins University, Baltimore, MD 21218.
Joseph N CapilatoDepartment of Chemistry, Johns Hopkins University, Baltimore, MD 21218.
Rakesh PaulDepartment of Chemistry, Johns Hopkins University, Baltimore, MD 21218.
Subrata PanjaT. C. Jenkins Department of Biophysics, Johns Hopkins University, Baltimore, MD 21218.
Taekjip HaDepartment of Biophysics and Biochemistry, Johns Hopkins University, Baltimore, MD 21205-2185.ORCID 0000-0003-2195-6258
Marc M GreenbergDepartment of Chemistry, Johns Hopkins University, Baltimore, MD 21218; mgreenberg@jhu.edu swoodson@jhu.edu.ORCID 0000-0002-5786-6118
Sarah A WoodsonT. C. Jenkins Department of Biophysics, Johns Hopkins University, Baltimore, MD 21218; mgreenberg@jhu.edu swoodson@jhu.edu.ORCID 0000-0003-0170-1987
Johns Hopkins University · USHoward Hughes Medical Institute · US

Funding

REGULATION OF LIPID METABOLISM IN E COLIR01GM034496 · NIGMS · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI ROCK, CHARLES O · 1985 to 2022
$9.2M
Repair, Replication, and Detection of Oxidatively Damaged DNAR01GM063028 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI GREENBERG, MARC M · 2002 to 2018
$5.4M
Mechanistic Studies of Nucleic Acid Damage and Their Applications.R01GM054996 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI GREENBERG, MARC M · 1997 to 2019
$5.4M
Single Molecule Studies of Nucleic Acids RemodelingR35GM122569 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI Taekjip Ha · 2017 to 2026
$3.5M
Acquisition of GE Typhoon FLA9500 Variable Mode ImagerS10OD021567 · OD · JOHNS HOPKINS UNIVERSITY · PI MCCAFFERY, J. MICHAEL · 2017 to 2017
$147k
Howard Hughes Medical InstituteNIGMS NIH HHS R01 GM034496NIGMS NIH HHS R01 GM054996NIGMS NIH HHS R01 GM063028NIGMS NIH HHS R35 GM122569NIH HHS S10 OD021567
6 · The paper itself

Abstract

Small ribozymes such as

Indexed as

Fluorescence Resonance Energy TransferNanotechnologyOryzaRNA, CatalyticRNA FoldingRNA, Catalyticnucleic acid chemistryphotocaged nucleotideribozyme catalysisRNA foldingsingle-molecule FRET

Identifiers

PMID32430319
PMCPMC7275738
OpenAlexW3026737954

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.