Evidence map›Paper›PMID 32430015›Full record

ReviewParasites & vectors2020

Equid infective Theileria cluster in distinct 18S rRNA gene clades comprising multiple taxa with unusually broad mammalian host ranges.

Richard P Bishop, Lowell S Kappmeyer, Cynthia K Onzere, David O Odongo, Naftaly Githaka, Kelly P Sears, Donald P Knowles, Lindsay M Fry

Open access · goldAbstract readReview
In one paragraph

Review in Parasites & vectors, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 29 citations in OpenAlex.

  1. Pathogens (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Genomic Characterization ofMicrobiology spectrum · 2023
    Article
  8. Article
  9. Tulathromycin and Diclazuril Lack Efficacy againstPathogens (Basel, Switzerland) · 2023
    Article
  10. Microorganisms · 2022
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Imidocarb Dipropionate Lacks Efficacy againstPathogens (Basel, Switzerland) · 2020
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Richard P BishopDepartment of Veterinary Microbiology and Pathology, Washington State University, P.O. Box 647040, Pullman, Washington, 99164, USA.
Lowell S KappmeyerAnimal Disease Research Unit, Agricultural Research Service, US Department of Agriculture, P.O. Box 646630, Pullman, WA, 99164, USA.
Cynthia K OnzereDepartment of Veterinary Microbiology and Pathology, Washington State University, P.O. Box 647040, Pullman, Washington, 99164, USA.
David O OdongoBiosciences Eastern and Central Africa-International Livestock Research Institute (BecA-ILRI) Hub, P.O. Box 30709, Nairobi, 00100, Kenya.
Naftaly GithakaBiosciences Eastern and Central Africa-International Livestock Research Institute (BecA-ILRI) Hub, P.O. Box 30709, Nairobi, 00100, Kenya.
Kelly P SearsDepartment of Veterinary Microbiology and Pathology, Washington State University, P.O. Box 647040, Pullman, Washington, 99164, USA.
Donald P KnowlesDepartment of Veterinary Microbiology and Pathology, Washington State University, P.O. Box 647040, Pullman, Washington, 99164, USA.
Lindsay M FryDepartment of Veterinary Microbiology and Pathology, Washington State University, P.O. Box 647040, Pullman, Washington, 99164, USA. Lindsay.Fry@usda.gov.
Washington State University · USAgricultural Research Service · USInternational Livestock Research Institute · KE

Funding

Agricultural Research Service 2090-320000-034-00D
6 · The paper itself

Abstract

Equine theileriosis, a tick-transmitted disease caused by the hemoprotozoan parasites Theileria equi and Theileria haneyi, affects equids throughout tropical and subtropical regions of the world. It is a significant regulatory concern in non-endemic countries, where testing for equine theileriosis is required prior to horse import to prevent parasite entry. Within endemic areas, infection causes significant morbidity and mortality, leading to economic losses. No vaccine for equine theileriosis is available, and current drug treatment protocols are inconsistent and associated with significant side effects. Recent work has revealed substantial genetic variability among equine theileriosis organisms, and analysis of ribosomal DNA from affected animals around the world indicates that the organisms can be grouped into five distinct clades. As these diverse parasites are capable of infecting a wide range of both tick and mammalian hosts, movement of different equine Theileria species between endemic countries, and eventually into non-endemic countries, is a significant concern. Furthermore, the substantial genetic variability of these organisms will likely render currently utilized importation diagnostic tests unable to detect all equine Theileria spp. To this end, more complete characterization of these diverse parasites is critical to the continued global control of equine theileriosis. This review discusses current knowledge of equine Theileria spp. in this context, and highlights new opportunities and challenges for workers in this field.

Indexed as

Host SpecificityAnimalsGenetic VariationHorse DiseasesHorsesMammalsPhylogenyRNA, Ribosomal, 18STheileriaTheileriasisRNA, Ribosomal, 18SCladesEquine theileriosisPhylotypesTheileria equiTheileria haneyi

Identifiers

PMID32430015
PMCPMC7236219
OpenAlexW3027439716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.