Evidence map›Paper›PMID 32429939›Full record

ArticleBMC psychiatry2020

Predictors of remission from body dysmorphic disorder after internet-delivered cognitive behavior therapy: a machine learning approach.

Oskar Flygare, Jesper Enander, Erik Andersson, Brjánn Ljótsson, Volen Z Ivanov, David Mataix-Cols, Christian Rück

Registry-linked trialAbstract read
In one paragraph

Article in BMC psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02010619 (Internet Delivered Cognitive Behavior Therapy for Body Dysmorphic Disorder - a Randomized Controlled Trial), which is not on this map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02010619 nacompletednot on this map

Internet Delivered Cognitive Behavior Therapy for Body Dysmorphic Disorder - a Randomized Controlled Trial

TypeinterventionalSponsorKarolinska InstitutetRan2013 to 2015Enrolled94ConditionsBody Dysmorphic Disorder, BDDArmsCognitive behavior therapy, Supportive therapy
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  16. Artificial intelligence in psychodermatology: A brief report of applications and impact in clinical practice.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Oskar FlygareCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska University Hospital, Karolinska Institutet, M46, SE-141 86, Huddinge, Sweden. oskar.flygare@ki.se.ORCID 0000-0002-2017-3940
Jesper EnanderCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska University Hospital, Karolinska Institutet, M46, SE-141 86, Huddinge, Sweden.
Erik AnderssonCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska University Hospital, Karolinska Institutet, M46, SE-141 86, Huddinge, Sweden.
Brjánn LjótssonCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska University Hospital, Karolinska Institutet, M46, SE-141 86, Huddinge, Sweden.
Volen Z IvanovCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska University Hospital, Karolinska Institutet, M46, SE-141 86, Huddinge, Sweden.
David Mataix-ColsCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska University Hospital, Karolinska Institutet, M46, SE-141 86, Huddinge, Sweden.
Christian RückCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska University Hospital, Karolinska Institutet, M46, SE-141 86, Huddinge, Sweden.

Funding

Fredrik och Ingrid Thurings Stiftelse 2018-00390Karolinska Institutet Clinical Scientist Training Programme
6 · The paper itself

Abstract

backgroundPrevious attempts to identify predictors of treatment outcomes in body dysmorphic disorder (BDD) have yielded inconsistent findings. One way to increase precision and clinical utility could be to use machine learning methods, which can incorporate multiple non-linear associations in prediction models.

methodsThis study used a random forests machine learning approach to test if it is possible to reliably predict remission from BDD in a sample of 88 individuals that had received internet-delivered cognitive behavioral therapy for BDD. The random forest models were compared to traditional logistic regression analyses.

resultsRandom forests correctly identified 78% of participants as remitters or non-remitters at post-treatment. The accuracy of prediction was lower in subsequent follow-ups (68, 66 and 61% correctly classified at 3-, 12- and 24-month follow-ups, respectively). Depressive symptoms, treatment credibility, working alliance, and initial severity of BDD were among the most important predictors at the beginning of treatment. By contrast, the logistic regression models did not identify consistent and strong predictors of remission from BDD.

conclusionsThe results provide initial support for the clinical utility of machine learning approaches in the prediction of outcomes of patients with BDD.

trial registrationClinicalTrials.gov ID: NCT02010619.

Indexed as

Internet-Based InterventionMachine LearningAdultBody Dysmorphic DisordersCognitive Behavioral TherapyFemaleHumansInternetMaleTreatment OutcomeBody dysmorphic disorderCognitive behaviour therapyInternetMachine learningPredictor

Identifiers

PMID32429939
PMCPMC7238519

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.