ArticlePolymers2020
Fabrication and Characterization of Hydrogels Based on Gelatinised Collagen with Potential Application in Tissue Engineering.
Article in Polymers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Smart responsive hydrogels combined with AI design for tumor therapy.Acta pharmaceutica Sinica. B · 2026Review
- Comparative analysis of collagen from different sources for wound and burn management.Biomaterials translational · 2026Article
- The Immobilization of Hyaluronic Acid in 3D Hydrogel Scaffolds Modulates Macrophage Polarization.Advanced biology · 2025Article
- A Robust Marine Collagen Peptide-Agarose 3D Culture System for In Vitro Modeling of Hepatocellular Carcinoma and Anti-Cancer Therapeutic Development.Marine drugs · 2025Article
- Article
- Fabrication and Biomedical Application of Alginate Composite Hydrogels in Bone Tissue Engineering: A Review.International journal of molecular sciences · 2024Review
- Unveiling the Impact of Gelation Temperature on the Rheological and Microstructural Properties of Type A Gelatin Hydrogels.Polymers · 2024Article
- Chitosan-Type-A-Gelatin Hydrogels Used as Potential Platforms in Tissue Engineering for Drug Delivery.Gels (Basel, Switzerland) · 2024Article
- Comparison of three-dimensional cell culture techniques of dedifferentiated liposarcoma and their integration with future research.Frontiers in cell and developmental biology · 2024Article
- The optimization of PLGA knitted mesh reinforced-collagen/chitosan scaffold for the healing of full-thickness skin defects.Journal of biomedical materials research. Part B, Applied biomaterials · 2023Article
- Type-A Gelatin-Based Hydrogel Infiltration and Degradation in Titanium Foams as a Potential Method for Localised Drug Delivery.Polymers · 2023Article
- Article
- Development and characterization of poultry collagen-based hybrid hydrogels for bone regeneration.Acta cirurgica brasileira · 2022Article
- Article
- Advocating Electrically Conductive Scaffolds with Low Immunogenicity for Biomedical Applications: A Review.Polymers · 2021Review
- Cryogenic Electron Microscopy Methodologies as Analytical Tools for the Study of Self-Assembled Pharmaceutics.Pharmaceutics · 2021Review
- Article
- Generation of Photopolymerized Microparticles Based on PEGDA Using Microfluidic Devices. Part 1. Initial Gelation Time and Mechanical Properties of the Material.Micromachines · 2021Article
- Rheological and Microstructural Evaluation of Collagen-Based Scaffolds Crosslinked with Fructose.Polymers · 2021Article
- Article
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Authors and funding
4 authors.
Funding
Abstract
Regenerative medicine is increasingly focused on the development of biomaterials that facilitate cell adhesion and proliferation through the use of natural polymers, which have better biocompatibility and biodegradability. In this way, the use of hydrogels has been considered as a potential option for tissue engineering due to their physical and chemical characteristics. However, few studies associate the raw materials properties and processing conditions with the final characteristics of hydrogels, which could condition their use as scaffolds for tissue engineering. In this context, the main objective of this work was the evaluation of type I collagen as raw material for the elaboration of hydrogels. In addition, gelation time, pH and temperature were evaluated as the most influential variables in the hydrogel processing method by rheological (time, strain and frequency sweep tests) and microstructural (Cryo-SEM) measurements. The results indicate that it is possible to obtain collagen hydrogels with adequate rheological and microstructural characteristics by selecting optimal processing conditions. However, further studies are necessary to assess their suitability for cell accommodation and growth.
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Registered trials
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