Evidence map›Paper›PMID 32429487›Full record

ArticleJournal of clinical medicine2020

Reproducibility of Ablated Volume Measurement Is Higher with Contrast-Enhanced Ultrasound than with B-Mode Ultrasound after Benign Thyroid Nodule Radiofrequency Ablation-A Preliminary Study.

Simone Schiaffino, Francesca Serpi, Duccio Rossi, Valerio Ferrara, Ciriaco Buonomenna, Marco Alì, Lorenzo Monfardini, Luca Maria Sconfienza, Giovanni Mauri

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Simone SchiaffinoRadiology Unit, IRCCS Policlinico San Donato, San Donato Milanese, 20097 Milan, Italy.ORCID 0000-0003-4243-888X
Francesca SerpiPost-graduate School in Radiodiagnostics, Università degli Studi di Milano, 20122 Milan, Italy.
Duccio RossiPost-graduate School in Radiodiagnostics, Università degli Studi di Milano, 20122 Milan, Italy.ORCID 0000-0002-6711-8084
Valerio FerraraPost-graduate School in Radiodiagnostics, Università degli Studi di Milano, 20122 Milan, Italy.
Ciriaco BuonomennaPost-graduate School in Radiodiagnostics, Università degli Studi di Milano, 20122 Milan, Italy.
Marco AlìRadiology Unit, IRCCS Policlinico San Donato, San Donato Milanese, 20097 Milan, Italy.ORCID 0000-0001-8156-7743
Lorenzo MonfardiniRadiology Unit, Fondazione Poliambulanza, 25124 Brescia, Italy.ORCID 0000-0002-7544-4170
Luca Maria SconfienzaIRCCS Istituto Ortopedico Galeazzi, 20161 Milan, Italy.ORCID 0000-0003-0759-8431
Giovanni MauriDivision of Interventional Radiology, European Institute of Oncology, IRCCS, 20141 Milan, Italy.ORCID 0000-0003-4726-2692
University of Milan · ITIRCCS Policlinico San Donato · ITFondazione Poliambulanza Istituto Ospedaliero · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The reproducibility of contrast-enhanced ultrasound (CEUS) and standard B-mode ultrasound in the assessment of radiofrequency-ablated volume of benign thyroid nodules was compared. A preliminary study was conducted on consecutive patients who underwent radiofrequency ablation (RFA) of benign thyroid nodules between 2014 and 2016, with available CEUS and B-mode post-ablation checks. CEUS and B-mode images were retrospectively evaluated by two radiologists to assess inter- and intra-observer agreement in the assessment of ablated volume (Bland-Altman test). For CEUS, the mean inter-observer difference (95% limits of agreement) was 0.219 mL (-0.372-0.809 mL); for B-mode, the mean difference was 0.880 mL (-1.655-3.414 mL). Reproducibility was significantly higher for CEUS (85%) than for B-mode (27%). Mean intra-observer differences (95% limits of agreement) were 0.013 mL (0.803-4.097 mL) for Reader 1 and 0.031 mL (0.763-3.931 mL) for Reader 2 using CEUS, while they were 0.567 mL (-2.180-4.317 mL, Reader 1) and 0.759 mL (-2.584-4.290 mL, Reader 2) for B-mode. Intra-observer reproducibility was significantly higher for CEUS (96% and 95%, for the two readers) than for B-mode (21% and 23%). In conclusion, CEUS had higher reproducibility and inter- and intra-observer agreement compared to conventional B-mode in the assessment of radiofrequency-ablated volume of benign thyroid nodules.

Indexed as

contrast-enhanced ultrasoundobserver variationradiofrequency ablationthyroid noduleultrasonography

Identifiers

PMID32429487
PMCPMC7291258
OpenAlexW3024300481

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.