Evidence map›Paper›PMID 32429429›Full record

Trial reportNutrients2020

Effect of Cod Residual Protein Supplementation on Markers of Glucose Regulation in Lean Adults: A Randomized Double-Blind Study.

Iselin Vildmyren, Alfred Halstensen, Adrian McCann, Øivind Midttun, Per Magne Ueland, Åge Oterhals, Oddrun Anita Gudbrandsen

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Iselin VildmyrenDietary Protein Research Group, Department of Clinical Medicine, University of Bergen, 5021 Bergen, Norway.
Alfred HalstensenK. Halstensen AS, P.O. Box 103, 5399 Bekkjarvik, Norway.
Adrian McCannBevital AS, Jonas Lies veg 87, 5021 Bergen, Norway.ORCID 0000-0002-5728-5321
Øivind MidttunBevital AS, Jonas Lies veg 87, 5021 Bergen, Norway.
Per Magne UelandBevital AS, Jonas Lies veg 87, 5021 Bergen, Norway.
Åge OterhalsNofima, P.B. 1425 Oasen, 5844 Bergen, Norway.ORCID 0000-0002-5378-4131
Oddrun Anita GudbrandsenDietary Protein Research Group, Department of Clinical Medicine, University of Bergen, 5021 Bergen, Norway.ORCID 0000-0001-5268-692X
Bevital (Norway) · NOUniversity of Bergen · NONofima · NO

Funding

CSRD VA 1The Regional Research Fund Western Norway No nr.The Research Council of Norway 252540
6 · The paper itself

Abstract

Large quantities of protein-rich cod residuals, which are currently discarded, could be utilized for human consumption. Although fish fillet intake is related to beneficial health effects, little is known about the potential health effects of consuming cod residual protein powder. Fifty lean adults were randomized to consume capsules with 8.1 g/day of cod residual protein (Cod-RP) or placebo capsules (Control group) for eight weeks, in this randomized, double-blind study. The intervention was completed by 40 participants. Fasting glucose and insulin concentrations were unaffected by Cod-RP supplementation, whereas plasma concentrations of α-hydroxybutyrate, β-hydroxybutyrate and acetoacetate all were decreased compared with the Control group. Trimethylamine N-oxide concentration in plasma and urine were increased in the Cod-RP group compared with the Control group. To conclude, the reduction in these potential early markers of impaired glucose metabolism following Cod-RP supplementation may indicate beneficial glucoregulatory effects of cod residual proteins. Trimethylamine N-oxide appears to be an appropriate biomarker of cod residual protein intake in lean adults.

Indexed as

Dietary SupplementsGadiformesAdultAnimalsBiomarkersBlood GlucoseDouble-Blind MethodFastingFemaleFish Proteins, DietaryHumansMaleMethylaminesMiddle AgedBiomarkersBlood GlucoseFish Proteins, DietaryMethylaminestrimethyloxaminebiomarkersdietary supplementsfish proteinhydroxybutyratemarine proteinTMAO

Identifiers

PMID32429429
PMCPMC7285039
OpenAlexW3025055422

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.