Evidence map›Paper›PMID 32429425›Full record

ArticleMarine drugs2020

The Effects of the Marine-Derived Polysaccharides Laminarin and Chitosan on Aspects of Colonic Health in Pigs Challenged with Dextran Sodium Sulphate.

Ruth Rattigan, John V O'Doherty, Stafford Vigors, Marion T Ryan, Rocco S Sebastiano, John J Callanan, Kevin Thornton, Gaurav Rajauria, Lekha M Margassery, Alan D W Dobson and 2 more

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. The MicroalgaeNutrients · 2022
    Article
  9. Anti-Inflammatory Effect of anInternational journal of molecular sciences · 2022
    Article
  10. Effects of Dietary Supplementation with Mushroom or Vitamin DAnimals : an open access journal from MDPI · 2021
    Article
  11. Review
  12. Evaluation of anFrontiers in microbiology · 2021
    Article
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Ruth RattiganSchool of Agriculture and Food Science, University College Dublin, Belfield, Dublin 4 D04 V1W8, Ireland.
John V O'DohertySchool of Agriculture and Food Science, University College Dublin, Belfield, Dublin 4 D04 V1W8, Ireland.ORCID 0000-0002-0906-4065
Stafford VigorsSchool of Agriculture and Food Science, University College Dublin, Belfield, Dublin 4 D04 V1W8, Ireland.ORCID 0000-0002-9304-2925
Marion T RyanSchool of Veterinary Medicine, University College Dublin, Belfield, Dublin 4 D04 V1W8, Ireland.
Rocco S SebastianoSchool of Veterinary Medicine, University College Dublin, Belfield, Dublin 4 D04 V1W8, Ireland.
John J CallananRoss University School of Veterinary Medicine, St. Kitts, West Indies.
Kevin ThorntonSchool of Veterinary Medicine, University College Dublin, Belfield, Dublin 4 D04 V1W8, Ireland.
Gaurav RajauriaSchool of Agriculture and Food Science, University College Dublin, Belfield, Dublin 4 D04 V1W8, Ireland.ORCID 0000-0001-5276-6962
Lekha M MargasserySchool of Microbiology, University College Cork, Cork City T12 YN60, Ireland.ORCID 0000-0003-3366-9520
Alan D W DobsonSchool of Microbiology, University College Cork, Cork City T12 YN60, Ireland.ORCID 0000-0002-7713-5574
Niall D O'LearySchool of Microbiology, University College Cork, Cork City T12 YN60, Ireland.
Torres SweeneySchool of Veterinary Medicine, University College Dublin, Belfield, Dublin 4 D04 V1W8, Ireland.ORCID 0000-0003-2639-395X
University College Dublin · IEUniversity College Cork · IERoss University School of Veterinary Medicine · KN

Funding

Department of Agriculture, Food and the Marine, Ireland 13/F/516Science Foundation Ireland 14/IA/2548
6 · The paper itself

Abstract

This study examined the effects of dietary supplementation with laminarin or chitosan on colonic health in pigs challenged with dextran sodium sulphate (DSS). Weaned pigs were assigned to: (1) a basal diet (n = 22); (2) a basal diet + laminarin (n = 10); and (3) a basal diet + chitosan (n = 10). On d35, the basal group was split, creating four groups: (1) the basal diet (control); (2) the basal diet + DSS; (3) the basal diet + laminarin + DSS; and (4) the basal diet + chitosan + DSS. From d39-42, the pigs were orally challenged with DSS. On d44, colonic tissue/digesta samples were collected. The basal DSS group had reduced growth, higher pathology score and an increased expression of

Indexed as

Dietary SupplementsAnimalsChitosanColitisDextransDisease Models, AnimalGlucansIntestinal MucosaMalePolysaccharidesProtective AgentsRandom AllocationSwineChitosanDextransGlucanslaminaranPolysaccharidesProtective Agentschitosancolitisdextran sodium sulphateinflammationlaminarinmicrobiota

Identifiers

PMID32429425
PMCPMC7281012
OpenAlexW3024582568

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.