Evidence map›Paper›PMID 32429372›Full record

ArticleSensors (Basel, Switzerland)2020

Fiberless, Multi-Channel fNIRS-EEG System Based on Silicon Photomultipliers: Towards Sensitive and Ecological Mapping of Brain Activity and Neurovascular Coupling.

Antonio Maria Chiarelli, David Perpetuini, Pierpaolo Croce, Giuseppe Greco, Leonardo Mistretta, Raimondo Rizzo, Vincenzo Vinciguerra, Mario Francesco Romeo, Filippo Zappasodi, Arcangelo Merla and 4 more

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 36 citations in OpenAlex.

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  17. Wearable, Integrated EEG-fNIRS Technologies: A Review.Sensors (Basel, Switzerland) · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 3 countries.

Antonio Maria ChiarelliDepartment of Neuroscience, Imaging and Clinical Sciences, Institute for Advanced Biomedical Technologies, University G. D'Annunzio of Chieti-Pescara, Via Luigi Polacchi 13, 66100 Chieti, Italy.ORCID 0000-0002-5347-8417
David PerpetuiniDepartment of Neuroscience, Imaging and Clinical Sciences, Institute for Advanced Biomedical Technologies, University G. D'Annunzio of Chieti-Pescara, Via Luigi Polacchi 13, 66100 Chieti, Italy.ORCID 0000-0003-1903-0501
Pierpaolo CroceDepartment of Neuroscience, Imaging and Clinical Sciences, Institute for Advanced Biomedical Technologies, University G. D'Annunzio of Chieti-Pescara, Via Luigi Polacchi 13, 66100 Chieti, Italy.ORCID 0000-0001-7279-3052
Giuseppe GrecoDepartment of Energy, Engineering and Mathematical Models, University of Palermo, Viale delle Scienze 9, 90128 Palermo, Italy.
Leonardo MistrettaDepartment of Energy, Engineering and Mathematical Models, University of Palermo, Viale delle Scienze 9, 90128 Palermo, Italy.
Raimondo RizzoDepartment of Energy, Engineering and Mathematical Models, University of Palermo, Viale delle Scienze 9, 90128 Palermo, Italy.
Vincenzo VinciguerraADG R&D, STMicroelectronics s.r.l., Stradale Primosole 50, 95121 Catania, Italy.ORCID 0000-0003-2188-4178
Mario Francesco RomeoADG R&D, STMicroelectronics s.r.l., Stradale Primosole 50, 95121 Catania, Italy.
Filippo ZappasodiDepartment of Neuroscience, Imaging and Clinical Sciences, Institute for Advanced Biomedical Technologies, University G. D'Annunzio of Chieti-Pescara, Via Luigi Polacchi 13, 66100 Chieti, Italy.
Arcangelo MerlaDepartment of Neuroscience, Imaging and Clinical Sciences, Institute for Advanced Biomedical Technologies, University G. D'Annunzio of Chieti-Pescara, Via Luigi Polacchi 13, 66100 Chieti, Italy.
Pier Giorgio FallicaADG R&D, STMicroelectronics s.r.l., Stradale Primosole 50, 95121 Catania, Italy.
Günter EdlingerGuger Technologies OG, Herbersteinstrasse 60, 8020 Graz, Austria.
Rupert Ortnerg.tec medical engineering Spain S.L., Calle Plom 5-7, 08038 Barcelona, Spain.
Giuseppe Costantino GiaconiaDepartment of Energy, Engineering and Mathematical Models, University of Palermo, Viale delle Scienze 9, 90128 Palermo, Italy.ORCID 0000-0003-2457-0772
University of Chieti-Pescara · ITUniversity of Palermo · ITSTMicroelectronics (Italy) · ITAnotec Engineering (Spain) · ESGuger Technologies (Austria) · AT

Funding

H2020, ECSEL-04-2015-Smart Health 692470
6 · The paper itself

Abstract

Portable neuroimaging technologies can be employed for long-term monitoring of neurophysiological and neuropathological states. Functional Near-Infrared Spectroscopy (fNIRS) and Electroencephalography (EEG) are highly suited for such a purpose. Their multimodal integration allows the evaluation of hemodynamic and electrical brain activity together with neurovascular coupling. An innovative fNIRS-EEG system is here presented. The system integrated a novel continuous-wave fNIRS component and a modified commercial EEG device. fNIRS probing relied on fiberless technology based on light emitting diodes and silicon photomultipliers (SiPMs). SiPMs are sensitive semiconductor detectors, whose large detection area maximizes photon harvesting from the scalp and overcomes limitations of fiberless technology. To optimize the signal-to-noise ratio and avoid fNIRS-EEG interference, a digital lock-in was implemented for fNIRS signal acquisition. A benchtop characterization of the fNIRS component showed its high performances with a noise equivalent power below 1 pW. Moreover, the fNIRS-EEG device was tested in vivo during tasks stimulating visual, motor and pre-frontal cortices. Finally, the capabilities to perform ecological recordings were assessed in clinical settings on one Alzheimer's Disease patient during long-lasting cognitive tests. The system can pave the way to portable technologies for accurate evaluation of multimodal brain activity, allowing their extensive employment in ecological environments and clinical practice.

Indexed as

Brain MappingElectroencephalographyNeurovascular CouplingSpectroscopy, Near-InfraredBrainHemodynamicsHumansclinical brain monitoringelectroencephalography (EEG)functional near infrared spectroscopy (fNIRS)multimodal neuroimagingneurovascular couplingsilicon photomultipliers

Identifiers

PMID32429372
PMCPMC7285196
OpenAlexW3024353932

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.