Evidence map›Paper›PMID 32429365›Full record

ArticleCancers2020

Detecting Endometrial Cancer by Blood Spectroscopy: A Diagnostic Cross-Sectional Study.

Maria Paraskevaidi, Camilo L M Morais, Katherine M Ashton, Helen F Stringfellow, Rhona J McVey, Neil A J Ryan, Helena O'Flynn, Vanitha N Sivalingam, Sarah J Kitson, Michelle L MacKintosh and 8 more

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06672341 (A Prospective, Open, Observational Clinical Study on Endometrial Cytology and Cervical Methylation Testing for Screening and Evaluating Fertility-Sparing Treatment in Endometrial Cancer), which is not on this map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06672341 not yet recruitingnot on this mapstarted 2024, after this paper: background citation

A Prospective, Open, Observational Clinical Study on Endometrial Cytology and Cervical Methylation Testing for Screening and Evaluating Fertility-Sparing Treatment in Endometrial Cancer

Typeobservational_patient_registrySponsorYulan RenRan2024 to 2026Enrolled200ConditionsEndometrial Cancer, Methylation, Cytology, Fertility PreservationArmsEndometrial Cytology Testing, Cervical Methylation Testing
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 45 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 7 institutions in 2 countries.

Maria ParaskevaidiSchool of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston PR1 2HE, UK.
Camilo L M MoraisSchool of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston PR1 2HE, UK.
Katherine M AshtonPathology Department, Lancashire Teaching Hospitals NHS Foundation, Preston PR2 9HT, UK.
Helen F StringfellowPathology Department, Lancashire Teaching Hospitals NHS Foundation, Preston PR2 9HT, UK.
Rhona J McVeyPathology Department, Manchester University Hospitals NHS Foundation Trust, Manchester M13 9WL, UK.
Neil A J RyanDivision of Cancer Sciences, University of Manchester, Manchester M13 9WL, UK.
Helena O'FlynnDivision of Cancer Sciences, University of Manchester, Manchester M13 9WL, UK.
Vanitha N SivalingamDivision of Cancer Sciences, University of Manchester, Manchester M13 9WL, UK.
Sarah J KitsonDivision of Cancer Sciences, University of Manchester, Manchester M13 9WL, UK.ORCID 0000-0003-2763-7370
Michelle L MacKintoshDepartment of Obstetrics and Gynaecology, Manchester University Hospitals NHS Foundation Trust, Manchester M13 9WL, UK.
Abigail E DerbyshireDepartment of Obstetrics and Gynaecology, Manchester University Hospitals NHS Foundation Trust, Manchester M13 9WL, UK.
Cecilia PowDivision of Cancer Sciences, University of Manchester, Manchester M13 9WL, UK.
Olivia RaglanDepartment of Metabolism, Institute of Reproductive and Developmental Biology, Digestion and Reproduction & Surgery and Cancer, Imperial College London, London W12 0HS, UK.ORCID 0000-0001-7815-6791
Kássio M G LimaDepartment of Chemistry, Biological Chemistry and Chemometrics, Federal University of Rio Grande do Norte, Natal 59072-970, Brazil.
Maria KyrgiouDepartment of Metabolism, Institute of Reproductive and Developmental Biology, Digestion and Reproduction & Surgery and Cancer, Imperial College London, London W12 0HS, UK.
Pierre L Martin-HirschDepartment of Obstetrics and Gynaecology, Lancashire Teaching Hospitals NHS Foundation, Preston PR2 9HT, UK.
Francis L MartinSchool of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston PR1 2HE, UK.
Emma J CrosbieDivision of Cancer Sciences, University of Manchester, Manchester M13 9WL, UK.ORCID 0000-0003-0284-8630
University of Manchester · GBLancashire Teaching Hospitals NHS Foundation Trust · GBUniversity of Lancashire · GBImperial College Healthcare NHS Trust · GBImperial College London · GBManchester University NHS Foundation Trust · GBUniversidade Federal do Rio Grande do Norte · BR

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 88881.128982/2016-01Department of Health NIHR-CS-012-009Genesis Research Trust P63522 WSCRMedical Research Council MR/M018431/1National Institute for Health Research IS-BRC-1215-20007National Institute for Health Research NIHR-CS-012-009Wellcome Trust 098670/Z/12/Z
6 · The paper itself

Abstract

Endometrial cancer is the sixth most common cancer in women, with a rising incidence worldwide. Current approaches for the diagnosis and screening of endometrial cancer are invasive, expensive or of moderate diagnostic accuracy, limiting their clinical utility. There is a need for cost-effective and minimally invasive approaches to facilitate the early detection and timely management of endometrial cancer. We analysed blood plasma samples in a cross-sectional diagnostic accuracy study of women with endometrial cancer (

Indexed as

blood diagnosticsendometrial cancerscreeningspectroscopy

Identifiers

PMID32429365
PMCPMC7281323
OpenAlexW3024002756

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.