Evidence map›Paper›PMID 32429269›Full record

ReviewInternational journal of molecular sciences2020

Epigenetic Alterations in Oesophageal Cancer: Expression and Role of the Involved Enzymes.

Nair Lopes, Margareta P Correia, Rui Henrique, Carmen Jerónimo

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  8. The relationship between P16Scientific reports · 2022
    Article
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  11. Frontiers in oncology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Nair LopesCancer Biology and Epigenetics Group, Research Centre of Portuguese Oncology Institute of Porto (GEBC CI-IPOP), Rua Dr. António Bernardino de Almeida, 4200-072 Porto, Portugal.
Margareta P CorreiaCancer Biology and Epigenetics Group, Research Centre of Portuguese Oncology Institute of Porto (GEBC CI-IPOP), Rua Dr. António Bernardino de Almeida, 4200-072 Porto, Portugal.
Rui HenriqueCancer Biology and Epigenetics Group, Research Centre of Portuguese Oncology Institute of Porto (GEBC CI-IPOP), Rua Dr. António Bernardino de Almeida, 4200-072 Porto, Portugal.
Carmen JerónimoCancer Biology and Epigenetics Group, Research Centre of Portuguese Oncology Institute of Porto (GEBC CI-IPOP), Rua Dr. António Bernardino de Almeida, 4200-072 Porto, Portugal.
Instituto Português de Oncologia Francisco Gentil · PTUniversidade do Porto · PT

Funding

FEDER ESTIMA-NORTE-01-0145-740 FEDER-000027Research Centre of IPO Porto (CI-IPOP) FBGEC-CI-IPOP-27-2016
6 · The paper itself

Abstract

Oesophageal cancer is a life-threatening disease, accounting for high mortality rates. The poor prognosis of this malignancy is mostly due to late diagnosis and lack of effective therapies for advanced disease. Epigenetic alterations may constitute novel and attractive therapeutic targets, owing to their ubiquity in cancer and their reversible nature. Herein, we offer an overview of the most important studies which compared differences in expression of enzymes that mediate epigenetic alterations between oesophageal cancer and normal mucosa, as well as

Indexed as

Epigenesis, GeneticGene Expression Regulation, NeoplasticEsophageal NeoplasmsHumansPublicationsepigeneticshistone modificationsmethylationoesophageal cancer

Identifiers

PMID32429269
PMCPMC7278932
OpenAlexW3025271696

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.