Evidence map›Paper›PMID 32429250›Full record

ArticleInternational journal of molecular sciences2020

Crossbridge Recruitment Capacity of Wild-Type and Hypertrophic Cardiomyopathy-Related Mutant Troponin-T Evaluated by X-ray Diffraction and Mechanical Study of Cardiac Skinned Fibers.

Maki Yamaguchi, Masako Kimura, Tetsuo Ohno, Naoya Nakahara, Nobutake Akiyama, Shigeru Takemori, Naoto Yagi

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Maki YamaguchiDepartment of Physiology, The Jikei University School of Medicine, Tokyo 105-8461, Japan.
Masako KimuraDepartment of Integrated Physiology, Kagawa Nutrition University, Saitama 350-0288, Japan.
Tetsuo OhnoDepartment of Sports Medicine, Teikyo Heisei University, Chiba 290-0193, Japan.
Naoya NakaharaDepartment of Physiology, The Jikei University School of Medicine, Tokyo 105-8461, Japan.
Nobutake AkiyamaCore Research Facilities for Basic Science, The Jikei University School of Medicine, Tokyo 105-8461, Japan.
Shigeru TakemoriDepartment of Physiology, The Jikei University School of Medicine, Tokyo 105-8461, Japan.
Naoto YagiSpectroscopy and Imaging Division, Japan Synchrotron Radiation Research Institute, SPring-8 679-5198 Hyogo, Japan.
Jikei University School of Medicine · JPKagawa Nutrition University · JPSPring-8 · JPTeikyo Heisei University · JP

Funding

Grants-in-aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology, Japan 847895undefined <span style="color:gray;font-size:10px;">undefined</span> 847895
6 · The paper itself

Abstract

X-ray diffraction and tension measurement experiments were conducted on rat left ventricular skinned fibers with or without "troponin-T treatment," which exchanges the endogenous troponin T/I/C complex with exogenous troponin-T. These experiments were performed to observe the structural changes in troponin-T within a fiber elicited by contractile crossbridge formation and investigate the abnormality of hypertrophic cardiomyopathy-related troponin-T mutants. The intensity of the troponin reflection at 1/38.5 nm

Indexed as

X-Ray DiffractionAnimalsCardiomyopathiesMaleMutationMyocardiumProtein DomainsRats, WistarTroponin TTroponin Tcardiomyopathyskinned fibertroponinX-ray diffraction

Identifiers

PMID32429250
PMCPMC7278983
OpenAlexW3024500166

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.