ArticleDiagnostics (Basel, Switzerland)2020
Performance of Radiomics Features in the Quantification of Idiopathic Pulmonary Fibrosis from HRCT.
Article in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Global landscape for pulmonary fibrosis treatment: a data-driven perspective from clinical trials.BMC pulmonary medicine · 2026Pooled it
- A Comparative Evaluation of Zero-Shot Performance of SAM, SAM2, MedSAM, and MedSAM2 Models on Lung Segmentation.Journal of imaging informatics in medicine · 2026Article
- Fibrosis in the Hiatus of Esophagus in Patients With Primary Esophageal Motor Disorders: Radiomic Analysis.Neurogastroenterology and motility · 2025Article
- Radiomics and Artificial Intelligence in Pulmonary Fibrosis.Journal of imaging informatics in medicine · 2025Review
- Radiomics-driven spectral profiling of six kidney stone types with monoenergetic CT reconstructions in photon-counting CT.European radiology · 2025Article
- Expert consensus on cancer treatment-related lung injury.Journal of thoracic disease · 2025Review
- Quantitative parameters of HRCT target scan to predict the risk of lung adenocarcinoma based on the detection of lung ground-glass nodules.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025Article
- Integrating Radiomics Signature into Clinical Pathway for Patients with Progressive Pulmonary Fibrosis.Diagnostics (Basel, Switzerland) · 2025Review
- Quantitative CT analysis of idiopathic pulmonary fibrosis and correlation with lung function study.BMC pulmonary medicine · 2024Article
- The Unveiled Triad: Clinical, Radiological and Pathological Insights into Hypersensitivity Pneumonitis.Journal of clinical medicine · 2024Review
- Prognostic significance of collagen content in solitary fibrous tumors of the central nervous system.Frontiers in oncology · 2024Article
- Radiomics-Assisted Computed Tomography-Based Analysis to Evaluate Lung Morphology Characteristics after Congenital Diaphragmatic Hernia.Journal of clinical medicine · 2023Article
- Impaired sliding between the lower esophageal sphincter and crural diaphragm (esophageal hiatus) in patients with achalasia esophagus.American journal of physiology. Gastrointestinal and liver physiology · 2023Article
- Beyond Visual Interpretation: Quantitative Analysis and Artificial Intelligence in Interstitial Lung Disease Diagnosis "Expanding Horizons in Radiology".Diagnostics (Basel, Switzerland) · 2023Review
- Phantom-based radiomics feature test-retest stability analysis on photon-counting detector CT.European radiology · 2023Article
- Performance of radiomics models derived from different CT reconstruction parameters for lung cancer risk prediction.BMC pulmonary medicine · 2023Article
- Radiomics in Cardiac Computed Tomography.Diagnostics (Basel, Switzerland) · 2023Review
- COVID-19 lung infection segmentation from chest CT images based on CAPA-ResUNet.International journal of imaging systems and technology · 2023Article
- Evaluation of radiomics feature stability in abdominal monoenergetic photon counting CT reconstructions.Scientific reports · 2022Article
- Radiomics for the Prediction of Response to Antifibrotic Treatment in Patients with Idiopathic Pulmonary Fibrosis: A Pilot Study.Diagnostics (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
15 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOur study assesses the diagnostic value of different features extracted from high resolution computed tomography (HRCT) images of patients with idiopathic pulmonary fibrosis. These features are investigated over a range of HRCT lung volume measurements (in Hounsfield Units) for which no prior study has yet been published. In particular, we provide a comparison of their diagnostic value at different Hounsfield Unit (HU) thresholds, including corresponding pulmonary functional tests.
methodsWe consider thirty-two patients retrospectively for whom both HRCT examinations and spirometry tests were available. First, we analyse the HRCT histogram to extract quantitative lung fibrosis features. Next, we evaluate the relationship between pulmonary function and the HRCT features at selected HU thresholds, namely -200 HU, 0 HU, and +200 HU. We model the relationship using a Poisson approximation to identify the measure with the highest log-likelihood.
resultsOur Poisson models reveal no difference at the -200 and 0 HU thresholds. However, inferential conclusions change at the +200 HU threshold. Among the HRCT features considered, the percentage of normally attenuated lung at -200 HU shows the most significant diagnostic utility.
conclusionsThe percentage of normally attenuated lung can be used together with qualitative HRCT assessment and pulmonary function tests to enhance the idiopathic pulmonary fibrosis (IPF) diagnostic process.
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