Evidence map›Paper›PMID 32429067›Full record

ArticleCells2020

TNFα Rescues Dendritic Cell Development in Hematopoietic Stem and Progenitor Cells Lacking C/EBPα.

Subramanian Anirudh, Angelika Rosenberger, Elke Schwarzenberger, Carolin Schaefer, Herbert Strobl, Armin Zebisch, Heinz Sill, Albert Wölfler

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Subramanian AnirudhDivision of Hematology, Medical University of Graz, Auenbruggerplatz 38, A-8036 Graz, Austria.ORCID 0000-0001-7102-9968
Angelika RosenbergerDivision of Hematology, Medical University of Graz, Auenbruggerplatz 38, A-8036 Graz, Austria.
Elke SchwarzenbergerDivision of Immunology and Pathophysiology, Otto Loewi Research Center for Vascular Biology, Immunology and Inflammation, Medical University of Graz, Heinrichstraße 31, A-8010 Graz, Austria.
Carolin SchaeferDivision of Hematology, Medical University of Graz, Auenbruggerplatz 38, A-8036 Graz, Austria.
Herbert StroblDivision of Immunology and Pathophysiology, Otto Loewi Research Center for Vascular Biology, Immunology and Inflammation, Medical University of Graz, Heinrichstraße 31, A-8010 Graz, Austria.
Armin ZebischDivision of Hematology, Medical University of Graz, Auenbruggerplatz 38, A-8036 Graz, Austria.ORCID 0000-0002-4861-7021
Heinz SillDivision of Hematology, Medical University of Graz, Auenbruggerplatz 38, A-8036 Graz, Austria.ORCID 0000-0003-0993-4371
Albert WölflerDivision of Hematology, Medical University of Graz, Auenbruggerplatz 38, A-8036 Graz, Austria.ORCID 0000-0002-3112-9857
Medical University of Graz · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dendritic cells (DCs) are crucial effectors of the immune system, which are formed from hematopoietic stem and progenitor cells (HSPCs) by a multistep process regulated by cytokines and distinct transcriptional mechanisms. C/EBPα is an important myeloid transcription factor, but its role in DC formation is not well defined. Using a

Indexed as

AnimalsCCAAT-Enhancer-Binding Protein-alphaChemokinesDendritic CellsHematopoietic Stem CellsMembrane ProteinsMice, Inbred C57BLMice, KnockoutTumor Necrosis Factor-alphaCCAAT-Enhancer-Binding Protein-alphaChemokinesflt3 ligand proteinMembrane ProteinsTumor Necrosis Factor-alphaC/EBPαdendritic cell developmentmonocytic dendritic cell progenitorsTNFα

Identifiers

PMID32429067
PMCPMC7291045
OpenAlexW3025257884

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.