Evidence map›Paper›PMID 32429063›Full record

Trial reportNutrients2020

Probiotic NVP-1703 Alleviates Allergic Rhinitis by Inducing IL-10 Expression: A Four-week Clinical Trial.

Min-Gyu Kang, Seung-Won Han, Hye-Ryun Kang, Seok-Jin Hong, Dong-Hyun Kim, Jeong-Hee Choi

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06372184 (Efficacy and Safety of Washed Microbiota Transplantation for Allergic Rhinitis), which is not on this map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06372184 nanot yet recruitingnot on this mapstarted 2024, after this paper: background citation

Efficacy and Safety of Washed Microbiota Transplantation for Allergic Rhinitis: A Randomized, Double-blind, Placebo-controlled Study

TypeinterventionalSponsorThe Second Hospital of Nanjing Medical UniversityRan2024 to 2029Enrolled32ConditionsRhinitis, AllergicArmsWashed Microbiota Transplantation, Placebo
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Immature Sword Bean (Nutrients · 2025
    Trial
  4. Frontiers in immunology · 2025
    Trial
  5. Efficacy ofJournal of Korean medical science · 2024
    Trial
  6. Trial
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Alterations of gut microbiome in eosinophilic chronic rhinosinusitis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Min-Gyu KangDepartment of Allergy and Clinical Immunology, Chungbuk National University Hospital, Cheongju 28644, Korea.ORCID 0000-0002-3239-4492
Seung-Won HanPB Business Department, Navipharm Inc., Suwon 16209, Korea.
Hye-Ryun KangDepartment of Internal Medicine, Division of Allergy and Clinical Immunology, Seoul National University Hospital, Seoul 03080, Korea.
Seok-Jin HongDepartment of Otorhinolaryngology-Head and Neck Surgery, Hallym University Dongtan Sacred Heart Hospital, Hwaseong 18450, Korea.
Dong-Hyun KimNeurobiota Research Center, College of Pharmacy, Kyung Hee University, Seoul 02453, Korea.
Jeong-Hee ChoiAllergy and Clinical Immunology Research Center, Hallym University College of Medicine, Chuncheon 24252, Korea.ORCID 0000-0002-0599-875X
Hallym University · KRChungbuk National University · KRKomipharm International (South Korea) · KRKyung Hee University · KRSeoul National University Hospital · KR

Funding

Hallym University Research Fund 2017 HURF-2017-76Medical Research Program of the National Research Foundation of Korea (NRF) funded by the Ministry of Science and ICT 2017M3A9G2049280
6 · The paper itself

Abstract

Although several recent studies reported that probiotics might be beneficial for allergic rhinitis (AR), the effect of probiotics on AR is not consistent and have not been reproduced between studies. We aimed to determine the efficacy and safety of probiotic NVP-1703, a mixture of

Indexed as

Bifidobacterium longumLactiplantibacillus plantarumAdultAgedDouble-Blind MethodFemaleHumansInterleukin-10MaleMiddle AgedProbioticsRhinitis, Allergic, PerennialTreatment OutcomeYoung AdultIL10 protein, humanInterleukin-10allergic rhinitisimmunoglobulin Einterleukin-10probiotics

Identifiers

PMID32429063
PMCPMC7284371
OpenAlexW3025445146

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.