Evidence map›Paper›PMID 32429039›Full record

ArticleBiomolecules2020

Novel Broccoli Sulforaphane-Based Analogues Inhibit the Progression of Pancreatic Cancer without Side Effects.

Christina Georgikou, Laura Buglioni, Maximilian Bremerich, Nico Roubicek, Libo Yin, Wolfgang Gross, Carsten Sticht, Carsten Bolm, Ingrid Herr

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Wogonin inhibits hepatoma cell proliferation by targeting miR-27b-5p/YWHAZ axis.Journal of biochemical and molecular toxicology · 2023
    Article
  9. Article
  10. Article
  11. A high-efficiency PEG-CaFrontiers in plant science · 2022
    Article
  12. Improving the Health-Benefits of Kales (Plants (Basel, Switzerland) · 2021
    Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Christina GeorgikouSection Surgical Research, Molecular OncoSurgery, Department of General, Visceral and Transplantation Surgery, University of Heidelberg, 69120 Heidelberg, Germany.
Laura BuglioniInstitute of Organic Chemistry, RWTH Aachen University, 52056 Aachen, Germany.
Maximilian BremerichInstitute of Organic Chemistry, RWTH Aachen University, 52056 Aachen, Germany.
Nico RoubicekInstitute of Organic Chemistry, RWTH Aachen University, 52056 Aachen, Germany.
Libo YinSection Surgical Research, Molecular OncoSurgery, Department of General, Visceral and Transplantation Surgery, University of Heidelberg, 69120 Heidelberg, Germany.
Wolfgang GrossSection Surgical Research, Molecular OncoSurgery, Department of General, Visceral and Transplantation Surgery, University of Heidelberg, 69120 Heidelberg, Germany.
Carsten StichtMedical Research Center, Medical Faculty Mannheim, University of Heidelberg, 69117 Mannheim, Germany.
Carsten BolmInstitute of Organic Chemistry, RWTH Aachen University, 52056 Aachen, Germany.ORCID 0000-0001-9415-9917
Ingrid HerrSection Surgical Research, Molecular OncoSurgery, Department of General, Visceral and Transplantation Surgery, University of Heidelberg, 69120 Heidelberg, Germany.ORCID 0000-0002-2389-6300
Heidelberg University · DERWTH Aachen University · DE

Funding

Deutsche Forschungsgemeinschaft HE 3186/15-1Deutsche Krebshilfe 111299Dietmar Hopp-Stiftung IHHanns A. Pielenz Stiftung IHHeidelberger Stiftung Chirurgie IHKlaus Tschira Stiftung IH
6 · The paper itself

Abstract

The naturally occurring isothiocyanate sulforaphane, found in

Indexed as

AnimalsAnticarcinogenic AgentsApoptosisBrassicaCaenorhabditis elegansChick EmbryoHep G2 CellsHumansIsothiocyanatesJurkat CellsLiverMicroRNAsNF-kappa BPancreatic NeoplasmsSulfoxidesAnticarcinogenic AgentsIsothiocyanatesMicroRNAsNF-kappa BsulforaphaneSulfoxidesbioactive agentsdrug developmentmicroRNA signalingNCI-60pancreatic cancersulforaphanesulfoximine

Identifiers

PMID32429039
PMCPMC7277136
OpenAlexW3024684896

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.