ReviewCurrent biology : CB2020
Pattern Formation and Complexity in Single Cells.
Review in Current biology : CB, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- An adaptable, self-organizing, single-cell morphology circuit optimizes suctorian predatory trap structure.Current biology : CB · 2026Article
- Data modeling the interplay between single-cell shape, single-cell protein expression, and tissue state.Cell reports methods · 2026Article
- A self-organizing single-cell morphology circuit optimizesbioRxiv : the preprint server for biology · 2025Article
- Specialized structure and function of the apical extracellular matrix at sense organs.Cells & development · 2024Review
- Dynamic microvilli sculpt bristles at nanometric scale.Nature communications · 2024Article
- A sex-specific switch in a single glial cell patterns the apical extracellular matrix.Current biology : CB · 2023Article
- Expression of Cell-Adhesion Molecules inInternational journal of molecular sciences · 2023Article
- A sex-specific switch in a single glial cell patterns the apical extracellular matrix.bioRxiv : the preprint server for biology · 2023Article
- Anterior-posterior pattern formation in ciliates.The Journal of eukaryotic microbiology · 2022Review
- Article
- Towards the Idea of Molecular Brains.International journal of molecular sciences · 2021Review
- Evolution of pigment cells and patterns: recent insights from teleost fishes.Current opinion in genetics & development · 2021Review
- Origins of eukaryotic excitability.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
In the context of animal or plant development, we tend to think of cells as small, simple, building blocks, such that complex patterns or shapes can only be constructed from large numbers of cells, with cells in different parts of the organism taking on different fates. However, cells themselves are far from simple, and often take on complex shapes with a remarkable degree of intracellular patterning. How do these patterns arise? As in embryogenesis, the development of structure inside a cell can be broken down into a number of basic processes. For each part of the cell, morphogenetic processes create internal structures such as organelles, which might correspond to organs at the level of a whole organism. Given that mechanisms exist to generate parts, patterning processes are required to ensure that the parts are distributed in the correct arrangement relative to the rest of the cell. Such patterning processes make reference to global polarity axes, requiring mechanisms for axiation which, in turn, require processes to break symmetry. These fundamental processes of symmetry breaking, axiation, patterning, and morphogenesis have been extensively studied in developmental biology but less so at the subcellular level. This review will focus on developmental processes that give eukaryotic cells their complex structures, with a focus on cytoskeletal organization in free-living cells, ciliates in particular, in which these processes are most readily apparent.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.