Evidence map›Paper›PMID 32428154›Full record

ArticleRevista da Associacao Medica Brasileira (1992)2020

Conditions of vulnerability to the inadequate treatment of bronchiolitis.

Kattia Cristina Neves, Sandra Elisabete Vieira

Erratum issuedOpen access · diamondAbstract read
PubMed Publisher
In one paragraph

Article in Revista da Associacao Medica Brasileira (1992), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kattia Cristina Neves. Mestre em Ciências pela Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brasil.ORCID http://orcid.org/0000-0001-5793-4507
Sandra Elisabete Vieira. Professora associada do Departamento de Pediatria da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brasil.ORCID http://orcid.org/0000-0001-5100-8713
Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo analyze clinical and demographic variables possibly associated with the prescriptions of non-recommended but routinely used therapies for infants with acute viral bronchiolitis.

methodsA cross-sectional study included hospitalized infants with bronchiolitis caused by the respiratory syncytial virus. Those with other associated infections and/or morbidities were excluded. The data were collected from medical records.

resultsAmong 120 cases, 90% used inhaled beta-agonists, 72.5% corticosteroids, 40% antibiotics, and 66.7% inhaled hypertonic saline solution. The use of bronchodilators did not present an independent association with another variable. More frequent use of corticosteroids was associated with low oximetry, longer hospitalization time, and age>3 months. Antibiotic therapy was associated with the presence of fever, longer hospitalization, and age>3 months. Inhaled hypertonic saline solution was associated with longer hospitalization time.

conclusionsNon-recommended prescriptions were frequent. Corticosteroid and antibiotic therapy were associated with signs of severity, as expected, but interestingly, they were more frequently used in infants above 3m, which suggested less safety in the diagnosis of viral bronchiolitis in these patients. The use of bronchodilators was even more worrying since they were indiscriminately used, without association with another variable related to the severity or characteristics of the host. The use of the inhaled hypertonic solution, although not associated with severity, seems to have implied a longer hospitalization time. The identification of these conditions of greater vulnerability to the prescription of inappropriate therapies contributes to the implantation of protocols for the bronchiolitis treatment, for continuing education and for analysis of the effectiveness of the strategies employed.

Indexed as

Acute DiseaseAdrenal Cortex HormonesAnti-Bacterial AgentsBronchiolitis, ViralBronchodilator AgentsChild, PreschoolCross-Sectional StudiesFemaleHospitalizationHumansInappropriate PrescribingInfantInfant, NewbornLogistic ModelsMaleMultivariate AnalysisAdrenal Cortex HormonesAnti-Bacterial AgentsBronchodilator AgentsSaline Solution, Hypertonic

Identifiers

PMID32428154
OpenAlexW3027954853

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.