Evidence map›Paper›PMID 32427996›Full record

ArticlePLoS neglected tropical diseases2020

Emergence of Zika virus infection in China.

Chuan-Min Zhou, Jian-Wei Liu, Rui Qi, Li-Zhu Fang, Xiang-Rong Qin, Hui-Ju Han, Rong-Can Mo, Hao Yu, Yong-Jun Jiao, Jian-Yan Lin and 1 more

Abstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  6. Viruses · 2024
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  7. The epidemiology ofFrontiers in public health · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chuan-Min ZhouState Key Laboratory of Virology, School of Health Sciences, Wuhan University, Wuhan, P.R. China.
Jian-Wei LiuState Key Laboratory of Virology, School of Health Sciences, Wuhan University, Wuhan, P.R. China.
Rui QiState Key Laboratory of Virology, School of Health Sciences, Wuhan University, Wuhan, P.R. China.
Li-Zhu FangState Key Laboratory of Virology, School of Health Sciences, Wuhan University, Wuhan, P.R. China.
Xiang-Rong QinState Key Laboratory of Virology, School of Health Sciences, Wuhan University, Wuhan, P.R. China.
Hui-Ju HanState Key Laboratory of Virology, School of Health Sciences, Wuhan University, Wuhan, P.R. China.
Rong-Can MoNanning Blood Center, Nanning, P.R. China.
Hao YuState Key Laboratory of Virology, School of Health Sciences, Wuhan University, Wuhan, P.R. China.
Yong-Jun JiaoInstitute of Pathogenic Microbiology, Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, China.
Jian-Yan LinThe Fourth People's Hospital of Nanning, Nanning, P.R. China.
Xue-Jie YuState Key Laboratory of Virology, School of Health Sciences, Wuhan University, Wuhan, P.R. China.ORCID 0000-0003-2665-3811

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Currently, Zika virus (ZIKV) is spreading across the world and no ZIKV infection cases have ever been reported in China. Here, we aimed to determine whether ZIKV infection exists in China. Blood samples of 273 healthy individuals were collected from Nanning City, Guangxi Province, China in March 2019. We found that 9.5% (26/273) and 1.8% (5/273) of healthy persons were positive to ZIKV total antibody (IgG and/or IgM) IgM antibody, respectively. All ZIKV positive plasma samples were negative to Dengue virus and West Nile virus. Among the ZIKV antibody positive plasma samples, 65.4% (17/26) exhibited neutralizing activity to ZIKV. Followed up studies showed that none had clinical symptoms of ZIKV infection and oversea experience. Together, our study indicates that endemic ZIKV infections emerge in China, which not only suggested that ZIKV posed a potential threat to public health in China, but also expand the ZIKV epidemic areas in East and Southeast Asia.

Indexed as

AdultAntibodies, NeutralizingAntibodies, ViralChinaFemaleHumansImmunoglobulin GImmunoglobulin MMaleMiddle AgedSeroepidemiologic StudiesYoung AdultZika VirusZika Virus InfectionAntibodies, NeutralizingAntibodies, ViralImmunoglobulin GImmunoglobulin M

Identifiers

PMID32427996
PMCPMC7263634

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.