ArticleScientific reports2020
A Micro-CT and Synchrotron Imaging Study of the Human Endolymphatic Duct with Special Reference to Endolymph Outflow and Meniere's Disease.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 18 citations in OpenAlex.
- The cochlear morphometry compendium: High-resolution synchrotron measurements and normative reference values.Journal of anatomy · 2026Article
- Inner Ear Anatomy Variations in Acute Low-Tone Sensorineural Hearing Loss and Unilateral Stage I/II Ménière's Disease: A Comparative Study.Diagnostics (Basel, Switzerland) · 2026Article
- Contrast Agent Uptake in Endolymphatic Sac and Duct: Inverse Relation to Endolymphatic Hydrops.The Laryngoscope · 2025Article
- Comparison of vestibular aqueduct visualization on computed tomography and magnetic resonance imaging in patients with Ménière's disease.BMC medical imaging · 2024Article
- Endolymphatic Duct and Sac Decompression: A New Life for an Old Technique.The journal of international advanced otology · 2023Article
- Comparison of radiological abnormalities between the jugular bulb and the vestibular aqueduct in patients with Ménière's disease.Frontiers in neurology · 2023Article
- Anatomical variation of inner ear may be a predisposing factor for unilateral Ménière's disease rather than for ipsilateral delayed endolymphatic hydrops.European radiology · 2022Article
- Endolymphatic duct and sac decompression: A new technique for Ménière's disease treatment.Surgical neurology international · 2022Article
- A Synchrotron and Micro-CT Study of the Human Endolymphatic Duct System: Is Meniere's Disease Caused by an Acute Endolymph Backflow?Frontiers in surgery · 2021Article
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Meniere's disease remains enigmatic, and has no treatment with sufficient evidence. The characteristic histopathological finding is endolymphatic hydrops, suggesting either an overproduction or decreased reabsorption of endolymph in the human inner ear. This study presents the first analysis of the vascular plexus around the human endolymphatic duct using micro computed tomography and coherent synchrotron radiation with phase contrast imaging. Using a software program, data were processed by volume-rendering with scalar opacity mapping to create transparent three-dimensional reconstructions. A rich vascular plexus was discovered around the endolymphatic duct that drained into collecting channels, linked to the vestibular venous outflow system. This network is believed to make up the principal route for endolymph outflow, and its associated malfunction may result in endolymphatic hydrops and Meniere's disease.
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