Evidence map›Paper›PMID 32427418›Full record

ArticleHead & neck2020

Head and neck paragangliomas: 30-year experience.

Cristina Valero, Ian Ganly, Jatin P Shah

Abstract read
In one paragraph

Article in Head & neck, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Multidisciplinary Management of Lateral Skull Base Paragangliomas: A 20-Year Experience.Journal of neurological surgery. Part B, Skull base · 2024
    Article
  8. [Paragangliomas of the head and neck].Radiologie (Heidelberg, Germany) · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. [Endothelial cells and fibroblasts mediate the microenvironmental regulatory network of carotid body paraganglioma].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Laryngeal Paraganglioma-A Case Report.Medicina (Kaunas, Lithuania) · 2024
    Article
  18. Intratumoral pseudoaneurysm in a carotid body tumor.Surgical neurology international · 2024
    Article
  19. Article
  20. An Update on Temporal Bone Paragangliomas.Current treatment options in oncology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Cristina ValeroHead and Neck Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0003-3397-2888
Ian GanlyHead and Neck Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
Jatin P ShahHead and Neck Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0002-6444-6592

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

backgroundWe aimed to review our experience and the changing trends in the management of head and neck paragangliomas (HNPG) over the last three decades.

methodsWe retrospectively reviewed 103 patients with HNPG treated at our center (1986-2017). We included patients treated with surgery, radiotherapy, and patients maintained under active surveillance.

resultsOf the surgically treated patients (n = 79), 20% (12/59) of the carotid body tumors (CBT) had a cranial nerve deficit as sequela compared to 95% (19/20) of the non-CBT. Radiotherapy controlled growth in all tumors treated with this modality (n = 10). Of the initially observed patients, 70% (14/20) remained stable and did not require additional treatment. Stratifying by decades, there was a progressive increase in patients initially attempted to be observed and a decrease in upfront surgery. No deaths attributable to the HNPG were encountered.

conclusionsSurgery is an effective treatment for CBT. Nonsurgical treatment should be considered for non-CBT.

Indexed as

Carotid Body TumorHead and Neck NeoplasmsParagangliomaParaganglioma, Extra-AdrenalHumansRetrospective StudiesTreatment Outcomecarotid body tumorcranial nerve neoplasmsglomus tumorhead and neck neoplasmsparagangliomas

Identifiers

PMID32427418
PMCPMC7725473

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.