Evidence map›Paper›PMID 32427380›Full record

Observational studyClinical cardiology2020

QTc interval evaluation in patients with right bundle branch block or bifascicular blocks.

Damir Erkapic, Gerrit Frommeyer, Niklas Brettner, Korkut Sözener, Harry J G M Crijns, Melchior Seyfarth, Christian W Hamm, Harilaos Bogossian

Open access · goldAbstract readComparative StudyMulticenter StudyObservational Study
In one paragraph

Observational study in Clinical cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. QTc interval measurement in patients with right bundle branch block: A practical method.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2023
    Article
  2. Determinants of severe QTFrontiers in psychiatry · 2023
    Article
  3. QTc evaluation in patients with bundle branch block.International journal of cardiology. Heart & vasculature · 2020
    Review
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Damir ErkapicDiakonie Klinikum Siegen, Department of Cardiology and Electrophysiology, Siegen, Germany.ORCID https://orcid.org/0000-0001-8251-1776
Gerrit FrommeyerClinic for Cardiology II - Electrophysiology, University Clinic of Münster, Münster, Germany.ORCID https://orcid.org/0000-0002-1431-9886
Niklas BrettnerDepartment of Cardiology and Angiology, University Clinic of Gießen, Medical Clinic I, Gießen, Germany.
Korkut SözenerDiakonie Klinikum Siegen, Department of Cardiology and Electrophysiology, Siegen, Germany.
Harry J G M CrijnsDepartment of Cardiology, Maastricht University Medical Center (MUMC+) and Cardiovascular Research, Institute Maastricht (CARIM), Maastricht, The Netherlands.
Melchior SeyfarthDepartment of Cardiology, Helios Klinikum Wuppertal, Wuppertal, Germany.
Christian W HammDepartment of Cardiology and Angiology, University Clinic of Gießen, Medical Clinic I, Gießen, Germany.
Harilaos BogossianDepartment of Cardiology, Maastricht University Medical Center (MUMC+) and Cardiovascular Research, Institute Maastricht (CARIM), Maastricht, The Netherlands.
Universitätsklinikum Gießen und Marburg · DEUniversity of Siegen · DEFernUniversität in Hagen · DEMaastricht University Medical Centre · NLUniversity Hospital Münster · DEWitten/Herdecke University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe right bundle branch block (RBBB) and the bifascicular blocks affect QRS duration in the right precordial leads, which are usually used for QT interval determination. Up to now, there is no clear recommendation how to determine QT interval in patients with RBBB or bifascicular block. HYPOTHESIS: The hypothesis of the present study was to evaluate the feasibility of a simple formula for RBBB and bifascicular block correction, thereby making it easier to determine the QTc interval.

methodsIn patients with intrinsic QRS duration <120 ms, artificial RBBB with either left posterior (LPFB) or left anterior fascicular block (LAFB), created by left ventricular pacing maneuvers, were corrected using the Bogossian formula (QTm) and afterward were heart rate corrected (QTmc). Heart rate correction was performed using different heart rate formulas in comparison to each other. The QTmc intervals were compared in each patient with the QTc interval during intrinsic rhythm.

resultsA total of scheduled 71 patients were included in this prospective multicenter observational comparative study. Compared to intrinsic QTc interval, the mean ΔQTmc interval by combination of the Bogossian and the Hodge formulas was -3 ± 24 ms in RBBB + LPFB (P = .44) and -6 ± 25 ms in RBBB + LAFB (P = .15). The Bogossian formula showed a significant deviation from the actual QTc interval with both the Bazett and the Fridericia formulas.

conclusionIn combination with the Hodge formula, the Boggosian formula delivered the best results in comparing the true QTc interval in narrow QRS with the QTmc interval in the presence of a bifascicular block.

Indexed as

Action PotentialsElectrocardiographyHeart RateAgedBundle-Branch BlockBundle of HisElectrophysiologic Techniques, CardiacFeasibility StudiesFemaleHumansMaleMiddle AgedModels, CardiovascularPredictive Value of TestsProspective StudiesSignal Processing, Computer-Assistedbifascicular blockBogossian formulalong QTQT formulaQT prolongationright bundle branch block

Identifiers

PMID32427380
PMCPMC7462182
OpenAlexW3028080215

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.