Evidence map›Paper›PMID 32427346›Full record

ArticleJournal of orthopaedic research : official publication of the Orthopaedic Research Society2021

Age-related changes in ACL morphology during skeletal growth and maturation are different between females and males.

Shayan Hosseinzadeh, Ata M Kiapour

Open access · greenAbstract read
In one paragraph

Article in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Pediatric ACL Injuries: A Current Concepts Review.Journal of clinical medicine · 2026
    Review
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  20. Sex-specific biomechanics and morphology of the anterior cruciate ligament during skeletal growth in a porcine model.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Shayan HosseinzadehDepartment of Orthopaedic Surgery, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.ORCID 0000-0002-5326-6852
Ata M KiapourDepartment of Orthopaedic Surgery, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.ORCID 0000-0001-7742-5769
Boston Children's Hospital · US

Funding

The Harvard Clinical and Translational Science CenterUL1TR002541 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2018 to 2022
$93.0M
Non-invasive Assessment of Ligament Healing, in VivoR01AR065462 · NIAMS · RHODE ISLAND HOSPITAL · PI FLEMING, BRADEN C, MURRAY, MARTHA M · 2014 to 2016
$2.1M
NIAMS NIH HHS R01 AR065462
6 · The paper itself

Abstract

Despite a well-established role of anterior cruciate ligament (ACL) anatomy on its biomechanics, little is known on how ACL anatomy develops and changes during skeletal growth. We hypothesized that ACL size and orientation will change by age during skeletal growth and maturation with different trends in males vs females. Magnetic resonance images of 269 unique knees (3-18 years old; 51% female) were used to measure ACL length, cross-sectional area, length-to-cross-sectional area ratio, and elevation angles. In both males and females, ACLs became longer, thicker, and more vertical in sagittal and coronal planes by increasing age (R

Indexed as

AgingSex FactorsAdolescentAge FactorsAnterior Cruciate LigamentBody SizeBone and BonesBone DevelopmentChildChild, PreschoolFemaleHumansImaging, Three-DimensionalKnee JointMagnetic Resonance ImagingMaleACLkneeligamentpediatricskeletal development

Identifiers

PMID32427346
PMCPMC7674212
OpenAlexW3027896364

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.