ArticleHypertension (Dallas, Tex. : 1979)2020
Gnotobiotic Rats Reveal That Gut Microbiota Regulates Colonic mRNA of
Abstract readLetter
In one paragraph
Article in Hypertension (Dallas, Tex. : 1979), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 1 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effectiveness of probiotics on COVID-19 prevention and treatment against mild COVID-19 in outpatient care: A systematic review.Nutrition and health · 2026Pooled it
- Probiotics and Bacteriocins Against SARS-CoV-2: Therapeutic Frontiers and Mechanistic Insights.Probiotics and antimicrobial proteins · 2026Review
- Fecal ACE and ACE2 Activities Reflect Intestinal Shedding and Microbiota Modulation of Renin-Angiotensin System.Biology · 2026Article
- Characterization of gut microbiota and metabolites in renal transplant recipients during COVID-19 and prediction of one-year allograft function.Journal of translational medicine · 2025Article
- Microbiota and Immunity during Respiratory Infections: Lung and Gut Affair.International journal of molecular sciences · 2024Review
- Gut microbiota in post-acute COVID-19 syndrome: not the end of the story.Frontiers in microbiology · 2024Review
- Genetically engineered Lactobacillus paracasei rescues colonic angiotensin converting enzyme 2 (ACE2) and attenuates hypertension in female Ace2 knock out rats.Pharmacological research · 2023Article
- Enteric nervous system as a target and source of SARS-CoV-2 and other viral infections.American journal of physiology. Gastrointestinal and liver physiology · 2023Review
- Gut Microbiota Dysbiosis in COVID-19: Modulation and Approaches for Prevention and Therapy.International journal of molecular sciences · 2023Review
- Oligosaccharides as Potential Regulators of Gut Microbiota and Intestinal Health in Post-COVID-19 Management.Pharmaceuticals (Basel, Switzerland) · 2023Review
- Association between Gut Microbiota and SARS-CoV-2 Infection and Vaccine Immunogenicity.Microorganisms · 2023Review
- The relationship between gut microbiota and COVID-19 progression: new insights into immunopathogenesis and treatment.Frontiers in immunology · 2023Review
- The metaproteome of the gut microbiota in pediatric patients affected by COVID-19.Frontiers in cellular and infection microbiology · 2023Article
- Development and management of gastrointestinal symptoms in long-term COVID-19.Frontiers in microbiology · 2023Review
- Six Decades of History of Hypertension Research at the University of Toledo: Highlighting Pioneering Contributions in Biochemistry, Genetics, and Host-Microbiota Interactions.Current hypertension reports · 2022Review
- Mechanisms Leading to Gut Dysbiosis in COVID-19: Current Evidence and Uncertainties Based on Adverse Outcome Pathways.Journal of clinical medicine · 2022Review
- Herbal medicine in the treatment of COVID-19 based on the gut-lung axis.Acupuncture and herbal medicine · 2022Review
- Symptomatology and microbiology of the gastrointestinal tract in post-COVID conditions.JGH open : an open access journal of gastroenterology and hepatology · 2022Review
- Gut and airway microbiota and their role in COVID-19 infection and pathogenesis: a scoping review.Infection · 2022Article
- Factors Modulating COVID-19: A Mechanistic Understanding Based on the Adverse Outcome Pathway Framework.Journal of clinical medicine · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors.
Tao YangFrom the Department of Physiology and Pharmacology, Microbiome Consortium, Center for Hypertension and Precision Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, OH (T.Y., S.C., P.S., B.M., X.C., J.-Y.Y., X.M., G.Z., J.M., R.G., B.S.Y., C.G.M., C.W., M.V.-K., B.J.).
Saroj ChakrabortyFrom the Department of Physiology and Pharmacology, Microbiome Consortium, Center for Hypertension and Precision Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, OH (T.Y., S.C., P.S., B.M., X.C., J.-Y.Y., X.M., G.Z., J.M., R.G., B.S.Y., C.G.M., C.W., M.V.-K., B.J.).
Piu SahaFrom the Department of Physiology and Pharmacology, Microbiome Consortium, Center for Hypertension and Precision Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, OH (T.Y., S.C., P.S., B.M., X.C., J.-Y.Y., X.M., G.Z., J.M., R.G., B.S.Y., C.G.M., C.W., M.V.-K., B.J.).
Blair MellFrom the Department of Physiology and Pharmacology, Microbiome Consortium, Center for Hypertension and Precision Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, OH (T.Y., S.C., P.S., B.M., X.C., J.-Y.Y., X.M., G.Z., J.M., R.G., B.S.Y., C.G.M., C.W., M.V.-K., B.J.).
Xi ChengFrom the Department of Physiology and Pharmacology, Microbiome Consortium, Center for Hypertension and Precision Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, OH (T.Y., S.C., P.S., B.M., X.C., J.-Y.Y., X.M., G.Z., J.M., R.G., B.S.Y., C.G.M., C.W., M.V.-K., B.J.).
Ji-Youn YeoFrom the Department of Physiology and Pharmacology, Microbiome Consortium, Center for Hypertension and Precision Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, OH (T.Y., S.C., P.S., B.M., X.C., J.-Y.Y., X.M., G.Z., J.M., R.G., B.S.Y., C.G.M., C.W., M.V.-K., B.J.).
Xue MeiFrom the Department of Physiology and Pharmacology, Microbiome Consortium, Center for Hypertension and Precision Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, OH (T.Y., S.C., P.S., B.M., X.C., J.-Y.Y., X.M., G.Z., J.M., R.G., B.S.Y., C.G.M., C.W., M.V.-K., B.J.).
Guannan ZhouFrom the Department of Physiology and Pharmacology, Microbiome Consortium, Center for Hypertension and Precision Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, OH (T.Y., S.C., P.S., B.M., X.C., J.-Y.Y., X.M., G.Z., J.M., R.G., B.S.Y., C.G.M., C.W., M.V.-K., B.J.).
Juthika MandalFrom the Department of Physiology and Pharmacology, Microbiome Consortium, Center for Hypertension and Precision Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, OH (T.Y., S.C., P.S., B.M., X.C., J.-Y.Y., X.M., G.Z., J.M., R.G., B.S.Y., C.G.M., C.W., M.V.-K., B.J.).
Rachel GolonkaFrom the Department of Physiology and Pharmacology, Microbiome Consortium, Center for Hypertension and Precision Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, OH (T.Y., S.C., P.S., B.M., X.C., J.-Y.Y., X.M., G.Z., J.M., R.G., B.S.Y., C.G.M., C.W., M.V.-K., B.J.).
Beng San YeohFrom the Department of Physiology and Pharmacology, Microbiome Consortium, Center for Hypertension and Precision Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, OH (T.Y., S.C., P.S., B.M., X.C., J.-Y.Y., X.M., G.Z., J.M., R.G., B.S.Y., C.G.M., C.W., M.V.-K., B.J.).
Vasanta Putluri
Danthasinghe Waduge Badrajee PiyarathnaArun Sreekumar (Department of Molecular Cell Biology, Dan L Duncan Comprehensive Cancer Center, and Center for Experimental Therapeutics and Metabolism, Baylor College of Medicine, Houston, TX) Vasanta Putluri (Advanced Technology Core, Baylor College of Medicine, Houston, TX) Nagireddy Putluri (Department of Molecular Cell Biology, Advanced Technology Core, and Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX) Department of Molecular and Cell Biology, Baylor College of Medicine, Houston, TX (D.W.B.P.).
Nagireddy Putluri
Cameron G McCarthyFrom the Department of Physiology and Pharmacology, Microbiome Consortium, Center for Hypertension and Precision Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, OH (T.Y., S.C., P.S., B.M., X.C., J.-Y.Y., X.M., G.Z., J.M., R.G., B.S.Y., C.G.M., C.W., M.V.-K., B.J.).
Camilla F WenceslauFrom the Department of Physiology and Pharmacology, Microbiome Consortium, Center for Hypertension and Precision Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, OH (T.Y., S.C., P.S., B.M., X.C., J.-Y.Y., X.M., G.Z., J.M., R.G., B.S.Y., C.G.M., C.W., M.V.-K., B.J.).
Arun Sreekumar
Andrew T GewirtzCenter for Inflammation, Immunity, and Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA (A.T.G.).
Matam Vijay-KumarFrom the Department of Physiology and Pharmacology, Microbiome Consortium, Center for Hypertension and Precision Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, OH (T.Y., S.C., P.S., B.M., X.C., J.-Y.Y., X.M., G.Z., J.M., R.G., B.S.Y., C.G.M., C.W., M.V.-K., B.J.).
Bina JoeFrom the Department of Physiology and Pharmacology, Microbiome Consortium, Center for Hypertension and Precision Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, OH (T.Y., S.C., P.S., B.M., X.C., J.-Y.Y., X.M., G.Z., J.M., R.G., B.S.Y., C.G.M., C.W., M.V.-K., B.J.).
Funding
Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI Michael M Ittmann · 2007 to 2026
$73.9MPathophysiology of TLR5KO ColitisR01DK083890 · NIDDK · GEORGIA STATE UNIVERSITY · PI GEWIRTZ, ANDREW T · 2010 to 2023
$5.0MDECONSTRUCTING INFLAMMATION AND ALTERED MICROBIOTA IN METABOLIC SYNDROMER01DK099071 · NIDDK · GEORGIA STATE UNIVERSITY · PI GEWIRTZ, ANDREW T · 2013 to 2024
$4.8MGenetic, Epigenetic and Dietary Salt effects on Microbiota and HypertensionR01HL143082 · NHLBI · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI JOE, BINA · 2018 to 2021
$2.6MInterplay between Dietary Fiber and Gut Microbiota in Hepatocellular CarcinomaR01CA219144 · NCI · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI VIJAY-KUMAR, MATAM · 2017 to 2021
$1.6MIntrarenal Arteries Sense N-formyl Peptides Leading to Vascular Injury in SepsisR00GM118885 · NIGMS · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI WENCESLAU, CAMILLA FERREIRA · 2019 to 2021
$746kNCI NIH HHS P30 CA125123NCI NIH HHS R01 CA219144NHLBI NIH HHS R01 HL143082NIDDK NIH HHS R01 DK083890NIDDK NIH HHS R01 DK099071NIGMS NIH HHS R00 GM118885
Abstract
PubMed holds no abstract for this paper.
Indexed as
ColitisColonCoronavirus InfectionsPandemicsPneumonia, ViralAngiotensin-Converting Enzyme 2AnimalsBetacoronavirusCorrelation of DataCOVID-19Gastrointestinal MicrobiomeGene Expression RegulationGerm-Free LifePeptidyl-Dipeptidase ARatsRNA, MessengerAce2 protein, ratAngiotensin-Converting Enzyme 2Peptidyl-Dipeptidase ARNA, Messenger
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.