ArticleJournal of natural products2020
Selective Chlorophyll Removal Method to "Degreen" Botanical Extracts.
Article in Journal of natural products, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Article
- Optimization of Natural Deep Eutectic Solvent-Assisted Extraction of Rosmarinic Acid fromMolecules (Basel, Switzerland) · 2025Article
- Analytical Approaches to the Rapid Characterisation of Marine Glycolipids in Bioproduct Discovery.Marine drugs · 2025Review
- Antioxidant and Anti-Inflammatory Benefits ofAntioxidants (Basel, Switzerland) · 2025Article
- Averrhoa carambola Leaf Extract Induces Apoptosis-Like Death with Increased ROS Generation in Leishmania donovani.Acta parasitologica · 2024Article
- Separation of flavonoids with significant biological activity fromRSC advances · 2023Article
- Evaluation of various clean-up sorbents in kale followed by LC-MS/MS analysis of pesticides.Food science and biotechnology · 2022Article
- Artificial photoactive chlorophyll conjugated vanadium carbide nanostructure for synergistic photothermal/photodynamic therapy of cancer.Journal of nanobiotechnology · 2022Article
- Betel (RSC advances · 2021Article
- A practical and easy-to-scale protocol for removing chlorophylls from leaf extracts.Applications in plant sciencesArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Chlorophylls are present in all extracts from the aerial parts of green plant materials. Chlorophylls may act as in vitro bioassay nuisance compounds, possibly preventing the reproducibility and accurate measurement of readouts due to their UV/vis absorbance, fluorescence properties, and tendency to precipitate in aqueous media. Despite the diversity of methods used traditionally to remove chlorophylls, details about their mode of operation, specificity, and reproducibility are scarce. Herein, we report a selective and efficient 45 min liquid-liquid/countercurrent chlorophyll cleanup method using Centrifugal Partition Chromatography (CPC) with a solvent system composed of hexanes-EtOAc-MeOH-water (5:5:5:5, v/v) in elution-extrusion mode. The broader utility of the method was assessed with four different extracts prepared from three well-characterized plant materials:
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Registered trials
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