Evidence map›Paper›PMID 32426930›Full record

ArticleJournal of neuroscience research2020

Parallel astrocyte calcium signaling modulates olfactory bulb responses.

Kevin Ung, Burak Tepe, Brandon Pekarek, Benjamin R Arenkiel, Benjamin Deneen

Open access · greenAbstract read
In one paragraph

Article in Journal of neuroscience research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.4field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 30 citations in OpenAlex.

  1. Developmental changes in CaScientific reports · 2026
    Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Neuron-Glial Interactions: Implications for Plasticity, Behavior, and Cognition.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Review
  8. Article
  9. Article
  10. Glial cells in the mammalian olfactory bulb.Frontiers in cellular neuroscience · 2024
    Review
  11. Sculpting Astrocyte Diversity through Circuits and Transcription.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2023
    Review
  12. Article
  13. AFrontiers in immunology · 2023
    Article
  14. Review
  15. Article
  16. Entrainment of Astrocytic and Neuronal CaNeuroscience bulletin · 2022
    Article
  17. Human Astrocytes Exhibit Tumor Microenvironment-, Age-, and Sex-Related Transcriptomic Signatures.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  18. Article
  19. "Tripartite Synapses" in Taste Buds: A Role for Type I Glial-like Taste Cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  20. Local and CNS-Wide Astrocyte Intracellular Calcium Signaling AttenuationThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kevin UngProgram in Developmental Biology, Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0002-2461-4379
Burak TepeProgram in Developmental Biology, Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0003-4371-2502
Brandon PekarekDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0001-8785-4196
Benjamin R ArenkielProgram in Developmental Biology, Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0001-9047-2420
Benjamin DeneenProgram in Developmental Biology, Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0002-6335-1081
Baylor College of Medicine · US

Funding

Preclinical and Clincial OutcomesP50HD103555 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI MIRJANA MALETIC-SAVATIC · 2020 to 2026
$9.9M
Steps towards a paternal gene activation therapy for Angelman syndromeU54HD083092 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI LEE, BRENDAN, NELSON, DAVID LOREN · 2014 to 2019
$7.8M
R01 Application:Genetically Dissecting Cholinergic Signaling in Body Weight Control.R01DK109934 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI Benjamin R Arenkiel, Qingchun Tong · 2016 to 2026
$5.4M
Transcriptional regulation of gliogenesis in the CNSR01NS071153 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI DENEEN, BENJAMIN · 2010 to 2022
$5.0M
Multilevel Analysis of Neuronal Computations Underlying the Robust Encoding of Sensory Information in the Mammalian Olfactory SystemUF1NS111692 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI ARENKIEL, BENJAMIN R, PFAFFINGER, PAUL · 2019 to 2019
$4.5M
MAPPING CONNECTIVITY ONTO POSTNATAL-BORN NEURONSR01NS078294 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI ARENKIEL, BENJAMIN R · 2012 to 2023
$3.6M
Decoding the role of diverse astrocyte populations in aging and ADRF1AG054111 · NIA · BAYLOR COLLEGE OF MEDICINE · PI DENEEN, BENJAMIN, ZHENG, HUI · 2016 to 2016
$3.1M
The Role of Local Astrocytes in Adult-born Neuron Circuit IntegrationF31NS089178 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI UNG, KEVIN · 2014 to 2016
$129k
NIA NIH HHS RF1 AG054111NICHD NIH HHS P50 HD103555NICHD NIH HHS U54 HD083092NIDDK NIH HHS R01 DK109934NINDS NIH HHS F31 NS089178NINDS NIH HHS R01 NS071153NINDS NIH HHS R01 NS078294NINDS NIH HHS UF1 NS111692
6 · The paper itself

Abstract

Astrocytes are the most abundant glial cell in the central nervous system. They modulate synaptic function through a variety of mechanisms, and yet remain relatively understudied with respect to overall neuronal circuit function. Exploiting the tractability of the mouse olfactory system, we manipulated astrocyte activity and examined how astrocytes modulate olfactory bulb responses. Toward this, we genetically targeted both astrocytes and neurons for in vivo widefield imaging of Ca

Indexed as

AnimalsAstrocytesCalciumCalcium SignalingMiceMice, Inbred C57BLMice, KnockoutNeuronsOdorantsOlfactory BulbOlfactory PathwaysCalciumastrocytecalciumcircuitDREADDin vivoolfactory

Identifiers

PMID32426930
PMCPMC8147697
OpenAlexW3026816953

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.