ArticleCerebral cortex (New York, N.Y. : 1991)2020
Spatiotemporal Integrity and Spontaneous Nonlinear Dynamic Properties of the Salience Network Revealed by Human Intracranial Electrophysiology: A Multicohort Replication.
Article in Cerebral cortex (New York, N.Y. : 1991), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 52 citations in OpenAlex.
- Neural self-organization during episodic encoding: deep recurrent effective connectivity from source-localized EEG.Frontiers in psychology · 2026Article
- Article
- Abnormal Enhanced Gamma Synchronization in the Default Mode Network Associated With Chronic Pain.European journal of neurology · 2025Article
- Article
- Electrophysiological dynamics of salience, default mode, and frontoparietal networks during episodic memory formation and recall: A multi-experiment iEEG replication.bioRxiv : the preprint server for biology · 2024Article
- Frequency-specific directed connectivity between the hippocampus and parietal cortex during verbal and spatial episodic memory: an intracranial EEG replication.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Hippocampal-parietal cortex causal directed connectivity during human episodic memory formation: Replication across three experiments.bioRxiv : the preprint server for biology · 2024Article
- Decision and response monitoring during working memory are sequentially represented in the human insula.iScience · 2023Article
- Impaired salience network switching in psychopathy.Behavioural brain research · 2023Article
- Review
- Connecting Circuits with Networks in Addiction Neuroscience: A Salience Network Perspective.International journal of molecular sciences · 2023Review
- Chronic Psychological Stress Disrupts Iron Metabolism and Enhances Hepatic Mitochondrial Function in Mice.Biological trace element research · 2023Article
- Neuronal dynamics of the default mode network and anterior insular cortex: Intrinsic properties and modulation by salient stimuli.Science advances · 2023Article
- Dynamic interactions between anterior insula and anterior cingulate cortex link perceptual features and heart rate variability during movie viewing.Network neuroscience (Cambridge, Mass.) · 2023Article
- Replicable patterns of causal information flow between hippocampus and prefrontal cortex during spatial navigation and spatial-verbal memory formation.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Review
- Spontaneous neuronal oscillations in the human insula are hierarchically organized traveling waves.eLife · 2022Article
- Electrophysiological foundations of the human default-mode network revealed by intracranial-EEG recordings during resting-state and cognition.NeuroImage · 2022Article
- Causal dynamics and information flow in parietal-temporal-hippocampal circuits during mental arithmetic revealed by high-temporal resolution human intracranial EEG.Cortex; a journal devoted to the study of the nervous system and behavior · 2022Article
- The role of PFC networks in cognitive control and executive function.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Review
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
The salience network (SN) plays a critical role in cognitive control and adaptive human behaviors, but its electrophysiological foundations and millisecond timescale dynamic temporal properties are poorly understood. Here, we use invasive intracranial EEG (iEEG) from multiple cohorts to investigate the neurophysiological underpinnings of the SN and identify dynamic temporal properties that distinguish it from the default mode network (DMN) and dorsolateral frontal-parietal network (FPN), two other large-scale brain networks that play important roles in human cognition. iEEG analysis of network interactions revealed that the anterior insula and anterior cingulate cortex, which together anchor the SN, had stronger intranetwork interactions with each other than cross-network interactions with the DMN and FPN. Analysis of directionality of information flow between the SN, DMN, and FPN revealed causal outflow hubs in the SN consistent with its role in fast temporal switching of network interactions. Analysis of regional iEEG temporal fluctuations revealed faster temporal dynamics and higher entropy of neural activity within the SN, compared to the DMN and FPN. Critically, these results were replicated across multiple cohorts. Our findings provide new insights into the neurophysiological basis of the SN, and more broadly, foundational mechanisms underlying the large-scale functional organization of the human brain.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.