ArticleCritical care explorations2020
Comparison of IV Insulin Dosing Strategies for Hyperkalemia in the Emergency Department.
Article in Critical care explorations, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
5 Versus 10 Units of Insulin in Hyperkalemia Management: Multi-center, Prospective, Double-blind, Non-inferiority, Randomized Control Trial.
Efficacy Of Lower-Dose Versus Conventional-Dose Of Insulin And Dextrose For Treatment Of Mild And Moderate Hyperkalaemia In Emergency Department: A Randomised, Triple-Blinded, Non-Inferiority Trial
Who cites it
7 citing papers in PubMed, 19 citations in OpenAlex.
- Intravenous Regular Insulin for Treatment of Hyperkalemia in Overweight Patients.Pharmacotherapy · 2025Article
- Strategies for optimization of hypoglycemia rat models.Animal models and experimental medicine · 2025Review
- Hyperkalemia Management with Intravenous Insulin in Patients with Reduced Kidney Function.Journal of clinical medicine · 2024Article
- A Retrospective Study of Patiromer as Adjunct to Insulin Therapy for Acute Hyperkalemia in the Emergency Department.Open access emergency medicine : OAEM · 2024Article
- Hypoglycaemia due to insulin therapy for the management of hyperkalaemia in hospitalised adults: A scoping review.PloS one · 2022Article
- Effects of estimated glomerular filtration rate and diabetes mellitus on the effect of insulin for treating hyperkalemia during anesthesia.Journal of anesthesia · 2021Article
- [Cardiac arrest under special circumstances].Notfall & rettungsmedizin · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
The objectives of this study were to evaluate the safety and efficacy of insulin dosing of less than 10 units versus 10 units in patients receiving hyperkalemia treatment.
designRetrospective single-center study.
settingEmergency department at a large academic medical center in the United States. PATIENTS: Seven hundred adults treated for hyperkalemia with IV regular insulin between April 1, 2013, and September 27, 2018.
interventionsPatients that received less than 10 units of insulin were compared to those that received 10 units of insulin. MEASUREMENTS AND MAIN
resultsPatients treated with less than 10 units had significantly lower frequency of hypoglycemia (11.2% vs 17.6%;
conclusionsPatients treated for hyperkalemia with insulin doses less than 10 units had reduced frequency of hypoglycemia; however, potassium reduction post treatment was more modest in these patients. These findings suggest providers choosing to administer 10 units IV insulin should ensure patients have adequate monitoring for hypoglycemia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.