ArticlePediatric quality & safety
The Vitals Risk Index-Retrospective Performance Analysis of an Automated and Objective Pediatric Early Warning System.
Article in Pediatric quality & safety. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Automated Features, Algorithms, and Technologies of Electronic Early Warning/Track-and-Trigger Systems: Systematic Review.Journal of medical Internet research · 2026Pooled it
- Performance of the Dutch Pediatric Early Warning Score: a nationwide study in academic, large teaching and general hospital contexts, using real-world data.BMJ paediatrics open · 2026Article
- Pediatric early warning score and unplanned readmission with influenza at emergency observation room.Frontiers in pediatrics · 2025Article
- Study protocol of a national multicentre prospective evaluation study assessing the validity and impact of the Dutch Paediatric Early Warning Score (PEWS) in the Netherlands.BMJ paediatrics open · 2024Article
- The Need for a Standard Outcome for Clinical Deterioration in Children's Hospitals.Pediatrics · 2023Article
- Multicenter validation of a deep-learning-based pediatric early-warning system for prediction of deterioration events.Acute and critical care · 2022Article
- A Comprehensive System for Identifying Patients With Type 1 Diabetes at Increased Risk for Diabetic Ketoacidosis at Texas Children's Hospital.Clinical diabetes : a publication of the American Diabetes Association · 2022Article
- Machine Learning-Based Systems for the Anticipation of Adverse Events After Pediatric Cardiac Surgery.Frontiers in pediatrics · 2022Article
- Reduction of Very Rapid Emergency Transfers to the Pediatric Intensive Care Unit.Pediatric quality & safetyArticle
- Improving Situational Awareness to Decrease Emergency ICU Transfers for Hospitalized Pediatric Cardiology Patients.Pediatric quality & safetyArticle
- A Quality Improvement Project to Promote Interdisciplinary Communication Using the Pediatric Early Warning System.Pediatric quality & safetyArticle
- The Nationwide Children's Hospital Blood and Marrow Transplant Index: A Quality Improvement Approach to Assess the Performance of a Pediatric Blood and Marrow Transplant Program.Pediatric quality & safetyArticle
- Pediatric ED Saves: Analyzing the ED Screen of Direct Admissions.Pediatric quality & safetyArticle
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPediatric in-hospital cardiac arrests and emergent transfers to the pediatric intensive care unit (ICU) represent a serious patient safety concern with associated increased morbidity and mortality. Some institutions have turned to the electronic health record and predictive analytics in search of earlier and more accurate detection of patients at risk for decompensation.
methodsObjective electronic health record data from 2011 to 2017 was utilized to develop an automated early warning system score aimed at identifying hospitalized children at risk of clinical deterioration. Five vital sign measurements and supplemental oxygen requirement data were used to build the Vitals Risk Index (VRI) model, using multivariate logistic regression. We compared the VRI to the hospital's existing early warning system, an adaptation of Monaghan's Pediatric Early Warning Score system (PEWS). The patient population included hospitalized children 18 years of age and younger while being cared for outside of the ICU. This dataset included 158 case hospitalizations (102 emergent transfers to the ICU and 56 "code blue" events) and 135,597 control hospitalizations.
resultsWhen identifying deteriorating patients 2 hours before an event, there was no significant difference between Pediatric Early Warning Score and VRI's areas under the receiver operating characteristic curve at false-positive rates ≤ 10% (pAUC
conclusionsThe VRI represents an objective, simple, and automated predictive analytics tool for identifying hospitalized pediatric patients at risk of deteriorating outside of the ICU setting.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.