Evidence map›Paper›PMID 32426497›Full record

ArticleScience advances2020

A novel proangiogenic B cell subset is increased in cancer and chronic inflammation.

Willem van de Veen, Anna Globinska, Kirstin Jansen, Alex Straumann, Terufumi Kubo, Daniëlle Verschoor, Oliver F Wirz, Francesc Castro-Giner, Ge Tan, Beate Rückert and 15 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 69 citations in OpenAlex.

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  10. Circulating Food Allergen-Specific Antibodies, Beyond IgG4, Are Elevated in Eosinophilic Esophagitis.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2025
    Article
  11. Review
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  13. Therapeutic potential of CD73Histology and histopathology · 2025
    Review
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  20. Type 2 immunity in allergic diseases.Cellular & molecular immunology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 5 institutions in 4 countries.

Willem van de VeenSwiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland.ORCID 0000-0001-9951-6688
Anna GlobinskaSwiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland.
Kirstin JansenSwiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland.
Alex StraumannSwiss EoE Clinic and EoE Research Network, Olten, Switzerland.
Terufumi KuboDepartment of Pathology, Sapporo Medical University School of Medicine, Sapporo, Japan.ORCID 0000-0001-9274-2551
Daniëlle VerschoorSwiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland.
Oliver F WirzSwiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland.ORCID 0000-0003-0377-6464
Francesc Castro-GinerSwiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland.ORCID 0000-0001-6111-0754
Ge TanSwiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland.ORCID 0000-0003-0026-8739
Beate RückertSwiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland.
Urs OchsnerSwiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland.
Marietta HerrmannAO Research Institute Davos, Davos, Switzerland.ORCID 0000-0002-2412-7474
Barbara StanićSwiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland.
Marloes van SplunterSwiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland.ORCID 0000-0002-8695-9030
Daan HuntjensSwiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland.ORCID 0000-0001-5354-9935
Alexandra WallimannSwiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland.
Rodney J Fonseca GuevaraSwiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland.
Hergen SpitsAIMM Therapeutics, Amsterdam, Netherlands.ORCID 0000-0003-3269-8338
Desislava IgnatovaDepartment of Dermatology, University Hospital Zurich, University of Zurich, Switzerland.
Yun-Tsan ChangDepartment of Dermatology, University Hospital Zurich, University of Zurich, Switzerland.
Christina FassnachtDepartment of Dermatology, University Hospital Zurich, University of Zurich, Switzerland.ORCID 0000-0001-5379-2687
Emmanuella GuenovaDepartment of Dermatology, University Hospital Zurich, University of Zurich, Switzerland.ORCID 0000-0001-5478-8735
Lukas FlatzInstitute of Immunobiology, Kantonsspital St. Gallen, Switzerland.ORCID 0000-0001-9683-8390
Cezmi A AkdisSwiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland.ORCID 0000-0001-8020-019X
Mübeccel AkdisSwiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland.ORCID 0000-0003-0554-9943
University of Zurich · CHAIMM Therapeutics (Netherlands) · NLAO Foundation · CHKantonsspital St. Gallen · CHSapporo Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

B cells contribute to immune responses through the production of immunoglobulins, antigen presentation, and cytokine production. Several B cell subsets with distinct functions and polarized cytokine profiles have been reported. In this study, we used transcriptomics analysis of immortalized B cell clones to identify an IgG4

Indexed as

B-Lymphocyte SubsetsEosinophilic EsophagitisMelanomaCytokinesHumansImmunoglobulin GInflammationIntegrin alpha2CytokinesImmunoglobulin GIntegrin alpha2

Identifiers

PMID32426497
PMCPMC7220305
OpenAlexW3025420163

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.