Evidence map›Paper›PMID 32426496›Full record

ArticleScience advances2020

Dlp-mediated Hh and Wnt signaling interdependence is critical in the niche for germline stem cell progeny differentiation.

Renjun Tu, Bo Duan, Xiaoqing Song, Ting Xie

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  10. Gut · 2023
    Article
  11. Gap junction-transported cAMP from the niche controls stem cell progeny differentiation.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Renjun TuStowers Institute for Medical Research, 1000 East 50th Street, Kansas City, MO 64110, USA.ORCID 0000-0003-2764-2575
Bo DuanStowers Institute for Medical Research, 1000 East 50th Street, Kansas City, MO 64110, USA.
Xiaoqing SongStowers Institute for Medical Research, 1000 East 50th Street, Kansas City, MO 64110, USA.
Ting XieStowers Institute for Medical Research, 1000 East 50th Street, Kansas City, MO 64110, USA.ORCID 0000-0003-4769-986X
Stowers Institute for Medical Research · US

Funding

Drosophila Transgenic RNAi Resource ProjectR01GM084947 · NIGMS · HARVARD MEDICAL SCHOOL · PI PERRIMON, NORBERT · 2008 to 2019
$9.8M
Investigation of Niche Control of Germline Stem Cell Lineage DifferentiationR01HD097664 · NICHD · STOWERS INSTITUTE FOR MEDICAL RESEARCH · PI XIE, TING · 2019 to 2020
$685k
NICHD NIH HHS R01 HD097664NIGMS NIH HHS R01 GM084947
6 · The paper itself

Abstract

Although multiple signaling pathways work synergistically in various niches to control stem cell self-renewal and differentiation, it remains poorly understood how they cooperate with one another molecularly. In the

Indexed as

Drosophila ProteinsWnt Signaling PathwayAnimalsBone Morphogenetic ProteinsCell DifferentiationDrosophilaFemaleGerm CellsStem Cell NicheStem CellsWnt ProteinsBone Morphogenetic ProteinsDrosophila ProteinsWnt Proteins

Identifiers

PMID32426496
PMCPMC7220319
OpenAlexW3024491709

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.