Evidence map›Paper›PMID 32426409›Full record

ArticleOrthopaedic journal of sports medicine2020

Risk of Deep Vein Thrombosis After Acute Achilles Tendon Rupture: A Secondary Analysis of a Randomized Controlled Trial Comparing Early Controlled Motion of the Ankle Versus Immobilization.

Kristoffer Weisskirchner Barfod, Emil Graakjær Nielsen, Beth Hærsted Olsen, Pablo Gustavo Vinicoff, Anders Troelsen, Per Holmich

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Orthopaedic journal of sports medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02015364 (Non-operative Treatment of Acute Achilles Tendon Rupture, Early Controlled Mobilization Compared With Immobilization), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02015364 nacompletednot on this map

Non-operative Treatment of Acute Achilles Tendon Rupture, Early Controlled Mobilization Compared With Immobilization: A Blinded Randomized, Controlled Trial

TypeinterventionalSponsorHvidovre University HospitalRan2014 to 2018Enrolled130ConditionsAchilles Tendon Rupture, Deep Vein ThrombosisArmsControlled early mobilization
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. The heel-rise work test overestimates the performed work with 21-25% after an Achilles tendon rupture.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2021
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kristoffer Weisskirchner BarfodSports Orthopedic Research Center-Copenhagen, Arthroscopic Center, Department of Orthopedic Surgery, Copenhagen University Hospital, Amager-Hvidovre, Hvidovre, Denmark.
Emil Graakjær NielsenDepartment of Radiology, Copenhagen University Hospital, Amager-Hvidovre, Hvidovre, Denmark.
Beth Hærsted OlsenDepartment of Radiology, Copenhagen University Hospital, Amager-Hvidovre, Hvidovre, Denmark.
Pablo Gustavo VinicoffDepartment of Radiology, Copenhagen University Hospital, Amager-Hvidovre, Hvidovre, Denmark.
Anders TroelsenDepartment of Orthopaedic Surgery, Clinical Orthopedic Research Amager-Hvidovre, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.
Per HolmichSports Orthopedic Research Center-Copenhagen, Arthroscopic Center, Department of Orthopedic Surgery, Copenhagen University Hospital, Amager-Hvidovre, Hvidovre, Denmark.
Hvidovre Hospital · DKAmager Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImmobilization of the ankle joint has been suggested as a key element in the pathogenesis leading to deep vein thrombosis (DVT). PURPOSE: To investigate whether early controlled ankle motion (ECM) could reduce the incidence of DVT compared with immobilization (IM) in the treatment of acute Achilles tendon rupture. STUDY

designRandomized controlled trial; Level of evidence, 2.

methodsPatients aged 18 to 70 years were eligible for inclusion, and treatment was nonoperative. The ECM group performed movements of the ankle 5 times a day from weeks 3 to 8 after rupture. The control group was immobilized for 8 weeks. The outcome measure was DVT diagnosed with color Doppler ultrasound for above- and below-knee DVT at 2 and 8 weeks. The Achilles tendon Total Rupture Score, the heel-rise work test, and the Copenhagen Achilles ultrasonographic Length Measurement were performed at 4-, 6-, and 12-month follow-up.

resultsA total of 189 patients were assessed for eligibility from February 2014 to December 2016. Of these, 130 were randomized: 68 patients were allocated to the ECM group and 62 to the IM group. All patients participated in follow-up at 8 weeks assessing for DVT. In total, 62 (47.7%) patients were diagnosed with DVT: 33 of 68 (48.5%) in the ECM group and 28 of 61 (46.8%) in the IM group (

conclusionWe found that 1 in 2 patients presented with DVT in nonoperative treatment of acute Achilles tendon rupture. The ECM protocol revealed no benefit versus IM in reducing the incidence of DVT. DVT did not influence functional and patient-reported outcomes the first year after rupture. D-dimer seems an inappropriate test for detection of DVT in patients with acute Achilles tendon rupture. REGISTRATION: NCT02015364 (ClinicalTrials.gov identifier).

Indexed as

acute Achilles tendon rupturedeep vein thrombosisDVTdynamic rehabilitationearly controlled motion

Identifiers

PMID32426409
PMCPMC7222258
OpenAlexW3022007430

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.