Evidence map›Paper›PMID 32426338›Full record

ArticleFrontiers in bioengineering and biotechnology2020

Development of Multifunctional Biopolymeric Auto-Fluorescent Micro- and Nanogels as a Platform for Biomedical Applications.

Arti Vashist, Venkata Atluri, Andrea Raymond, Ajeet Kaushik, Tiyash Parira, Zaohua Huang, Andriy Durygin, Asahi Tomitaka, Roozbeh Nikkhah-Moshaie, Atul Vashist and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Arti VashistDepartment of Immunology and Nanomedicine, Center for Personalized Nanomedicine, Herbert Wertheim College of Medicine, Institute of NeuroImmune Pharmacology, Florida International University, Miami, FL, United States.
Venkata AtluriDepartment of Immunology and Nanomedicine, Center for Personalized Nanomedicine, Herbert Wertheim College of Medicine, Institute of NeuroImmune Pharmacology, Florida International University, Miami, FL, United States.
Andrea RaymondDepartment of Immunology and Nanomedicine, Center for Personalized Nanomedicine, Herbert Wertheim College of Medicine, Institute of NeuroImmune Pharmacology, Florida International University, Miami, FL, United States.
Ajeet KaushikDepartment of Immunology and Nanomedicine, Center for Personalized Nanomedicine, Herbert Wertheim College of Medicine, Institute of NeuroImmune Pharmacology, Florida International University, Miami, FL, United States.
Tiyash PariraDepartment of Immunology and Nanomedicine, Center for Personalized Nanomedicine, Herbert Wertheim College of Medicine, Institute of NeuroImmune Pharmacology, Florida International University, Miami, FL, United States.
Zaohua HuangDepartment of Immunology and Nanomedicine, Center for Personalized Nanomedicine, Herbert Wertheim College of Medicine, Institute of NeuroImmune Pharmacology, Florida International University, Miami, FL, United States.
Andriy DuryginCeSMEC, Florida International University, Miami, FL, United States.
Asahi TomitakaDepartment of Immunology and Nanomedicine, Center for Personalized Nanomedicine, Herbert Wertheim College of Medicine, Institute of NeuroImmune Pharmacology, Florida International University, Miami, FL, United States.
Roozbeh Nikkhah-MoshaieDepartment of Immunology and Nanomedicine, Center for Personalized Nanomedicine, Herbert Wertheim College of Medicine, Institute of NeuroImmune Pharmacology, Florida International University, Miami, FL, United States.
Atul VashistDepartment of Biotechnology, All India Institute of Medical Science, New Delhi, India.
Marisela AgudeloDepartment of Immunology and Nanomedicine, Center for Personalized Nanomedicine, Herbert Wertheim College of Medicine, Institute of NeuroImmune Pharmacology, Florida International University, Miami, FL, United States.
Hitendra S ChandDepartment of Immunology and Nanomedicine, Center for Personalized Nanomedicine, Herbert Wertheim College of Medicine, Institute of NeuroImmune Pharmacology, Florida International University, Miami, FL, United States.
Ilyas SaytashevDepartment of Biomedical Engineering, Florida International University, Miami, FL, United States.
Jessica C Ramella-RomanDepartment of Biomedical Engineering, Florida International University, Miami, FL, United States.
Madhavan NairDepartment of Immunology and Nanomedicine, Center for Personalized Nanomedicine, Herbert Wertheim College of Medicine, Institute of NeuroImmune Pharmacology, Florida International University, Miami, FL, United States.
Florida International University · USAll India Institute of Medical Sciences · INDepartment of Biotechnology · INDr. Herbert & Nicole Wertheim Family Foundation · US

Funding

To evaluate the role of cannabinoid signaling during the comorbidity of HIV and Alzheimer¿s disease in the context of HIV-associated cognitive disordersR01DA040537 · NIDA · FLORIDA INTERNATIONAL UNIVERSITY · PI NAIR, MADHAVAN P. · 2015 to 2019
$3.0M
Cocaine in the Neuropathogenesis of HIV infection: Role of HDAC2R01DA034547 · NIDA · FLORIDA INTERNATIONAL UNIVERSITY · PI NAIR, MADHAVAN P. · 2013 to 2018
$1.8M
Multifunctional Nanocarrier to Eradicate HIV from latently infected CNS cells andR01DA037838 · NIDA · FLORIDA INTERNATIONAL UNIVERSITY · PI NAIR, MADHAVAN P. · 2014 to 2018
$1.8M
NIDA NIH HHS R01 DA034547NIDA NIH HHS R01 DA037838NIDA NIH HHS R01 DA040537
6 · The paper itself

Abstract

The emerging field of theranostics for advanced healthcare has raised the demand for effective and safe delivery systems consisting of therapeutics and diagnostics agents in a single monarchy. This requires the development of multi-functional bio-polymeric systems for efficient image-guided therapeutics. This study reports the development of size-controlled (micro-to-nano) auto-fluorescent biopolymeric hydrogel particles of chitosan and hydroxyethyl cellulose (HEC) synthesized using water-in-oil emulsion polymerization technique. Sustainable resource linseed oil-based polyol is introduced as an element of hydrophobicity with an aim to facilitate their ability to traverse the blood-brain barrier (BBB). These nanogels are demonstrated to have salient features such as biocompatibility, stability, high cellular uptake by a variety of host cells, and ability to transmigrate across an

Indexed as

biopolymersmicrogelsnanogelsnanomedicinetheranostics

Identifiers

PMID32426338
PMCPMC7203429
OpenAlexW3015494221

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.