ArticleGlobal advances in health and medicine2020
Pilot Trial of a Noninvasive Closed-Loop Neurotechnology for Stress-Related Symptoms in Law Enforcement: Improvements in Self-Reported Symptoms and Autonomic Function.
Article in Global advances in health and medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 13 citations in OpenAlex.
- Randomized, controlled clinical trial of acoustic stimulation to reduce postconcussive symptoms.Annals of clinical and translational neurology · 2024Trial
- Brain State-Dependent Non-Invasive Neurostimulation with EEG Feedback: Achievements and Prospects (Review).Sovremennye tekhnologii v meditsine · 2023Review
- A review of workplace mental health interventions and their implementation in public safety organizations.International archives of occupational and environmental health · 2022Review
- Correction of Stress-Induced States Using Sensory Stimulation Automatically Modulated by Endogenous Human Rhythms.Neuroscience and behavioral physiology · 2022Article
- Closed-Loop Adaptive Neurostimulation Technologies in Cognitive Rehabilitation of High-Tech Specialists.Sovremennye tekhnologii v meditsine · 2022Article
- Human Body Rhythms in the Development of Non-Invasive Methods of Closed-Loop Adaptive Neurostimulation.Journal of personalized medicine · 2021Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundLaw enforcement officers have decreased life expectancy, attributed to work-related exposure to traumatic stress and circadian disruption. Autonomic dysregulation is reported with traumatic stress and chronic insomnia.
objectiveWe explore potential benefits for reduced symptoms related to stress and insomnia and improved autonomic function associated with open label use of high-resolution, relational, resonance-based, electroencephalic mirroring (HIRREM®), in a cohort of sworn law enforcement personnel.
methodsClosed-loop noninvasive therapies utilizing real-time monitoring offer a patient-centric approach for brain-based intervention. HIRREM® is a noninvasive, closed-loop, allostatic, neurotechnology that echoes specific brain frequencies in real time as audible tones to support self-optimization of brain rhythms. Self-report symptom inventories done before and after HIRREM included insomnia (ISI), depression (CES-D), traumatic stress (PCL-C), anxiety (GAD-7), perceived stress (PSS), and quality of life (EQ-5D). Ten-minute recordings of heart rate and blood pressure allowed analysis of baroreflex sensitivity (BRS) and heart rate variability (HRV).
resultsFifteen participants (1 female), mean (SD) age 45.7 (5.6), received 12.2 (2.7) HIRREM sessions, over 7.9 in-office days. Data were collected at baseline, and at 22.8 (9.2), and 67.2 (14.1) days after intervention. All symptom inventories improved significantly (
conclusionThese pilot data provide the first report of significant symptom reductions, and associated improvement in measures of autonomic cardiovascular regulation, with the use of HIRREM in a cohort of law enforcement personnel. Randomized clinical trials are warranted.
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Registered trials
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