ArticleClinical and translational allergy2020
EAACI Task force Clinical epidemiology of anaphylaxis: experts' perspective on the use of adrenaline autoinjectors in Europe.
Article in Clinical and translational allergy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 21 citations in OpenAlex.
- Optimizing Adrenaline Administration in Anaphylaxis: Clinical Practice Considerations and Safety Insights.Clinical and translational allergy · 2025Review
- 10 practical priorities to prevent and manage serious allergic reactions: GAClinical and translational allergy · 2024Review
- Anaphylaxis management in a French pediatric emergency department: Lessons from the ANA-PED study.Clinical and translational allergy · 2023Article
- The 2020 update on anaphylaxis in paediatric population.Postepy dermatologii i alergologii · 2022Review
- The Economic Burden of Food Allergy: What We Know and What We Need to Learn.Current treatment options in allergy · 2022Review
- Latex Allergy: Current Status and Future Perspectives.Journal of asthma and allergy · 2020Review
- AlergiaPT: A Portuguese media campaign to inspire people with allergies to make a positive change in their life.Porto biomedical journalArticle
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Authors and funding
7 authors at 7 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWorldwide, guidelines recommend the use of adrenaline autoinjectors (AAIs) for self-medication in patients who experience severe allergic reaction. The European Medical Agency recommends the prescription of two AAIs, which should be carried by patients at all times. The European Academy of Allergy and Clinical Immunology guidelines propose to prescribe a second AAI under some defined conditions. In the present study, we aimed to examine the adherence to these guidelines and prescription behavior of allergy experts regarding the number of AAIs prescribed for a given patient.
methodsA standardized questionnaire was applied to the participants of the 5th International Conference of the Network of Online Registration for Anaphylaxis (NORA e. V.). Twenty-six experts (medical doctors with at least 2 years of experience in the field of anaphylaxis) answered the questions regarding the number of autoinjectors prescribed and the reasons influencing their decisions.
resultsSixty-eight percent of the experts usually prescribed one AAI, while 32% prescribed two. The pediatricians and physicians with less experience tended to prescribe two autoinjectors more frequently. The experts were more likely to prescribe two adrenaline autoinjectors if the patient was a child, had a previous severe reaction, had mastocytosis, asthma, cardiovascular disease, or high body weight, or lived far from the emergency department.
conclusionOur data confirm the lack of consensus regarding the number of AAIs to prescribe. Despite the European Medical Agency recommendation, the majority of allergy experts prescribed one autoinjector per patient. However, under distinct circumstances (e.g. mastocytosis, asthma, excess body weight, a history of severe anaphylaxis, or restricted access to immediate emergency), experts tended to prescribe more AAIs, which is in accordance with the European Academy of Allergy and Clinical Immunology guidelines.
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