Evidence map›Paper›PMID 32425934›Full record

ArticleFrontiers in immunology2020

Platelet Toll-Like Receptors Mediate Thromboinflammatory Responses in Patients With Essential Thrombocythemia.

Cecilia P Marín Oyarzún, Ana C Glembotsky, Nora P Goette, Paola R Lev, Geraldine De Luca, María C Baroni Pietto, Beatriz Moiraghi, Miguel A Castro Ríos, Angeles Vicente, Rosana F Marta and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 60 citations in OpenAlex.

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  7. Beyond hemostasis, the immunomodulatory nature of platelets.Research and practice in thrombosis and haemostasis · 2025
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  19. [Recent research on platelet-leukocyte aggregates and their role in the pathogenesis of Kawasaki disease].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2023
    Review
  20. Sepsis - it is all about the platelets.Frontiers in immunology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Cecilia P Marín OyarzúnInstitute of Medical Research A. Lanari, School of Medicine, University of Buenos Aires, Buenos Aires, Argentina.
Ana C GlembotskyInstitute of Medical Research A. Lanari, School of Medicine, University of Buenos Aires, Buenos Aires, Argentina.
Nora P GoetteInstitute of Medical Research A. Lanari, School of Medicine, University of Buenos Aires, Buenos Aires, Argentina.
Paola R LevInstitute of Medical Research A. Lanari, School of Medicine, University of Buenos Aires, Buenos Aires, Argentina.
Geraldine De LucaInstitute of Medical Research A. Lanari, School of Medicine, University of Buenos Aires, Buenos Aires, Argentina.
María C Baroni PiettoInstitute of Medical Research A. Lanari, School of Medicine, University of Buenos Aires, Buenos Aires, Argentina.
Beatriz MoiraghiDepartment of Hematology, Hospital General de Agudos José María Ramos Mejía, Buenos Aires, Argentina.
Miguel A Castro RíosConsultorios Hematológicos, Buenos Aires, Argentina.
Angeles VicenteDepartment of Hematology, Hospital Alemán, Buenos Aires, Argentina.
Rosana F MartaInstitute of Medical Research A. Lanari, School of Medicine, University of Buenos Aires, Buenos Aires, Argentina.
Mirta SchattnerLaboratory of Experimental Thrombosis, Institute of Experimental Medicine (IMEX)- CONICET, National Academy of Medicine, Buenos Aires, Argentina.
Paula G HellerInstitute of Medical Research A. Lanari, School of Medicine, University of Buenos Aires, Buenos Aires, Argentina.
University of Buenos Aires · ARConsejo Nacional de Investigaciones Científicas y Técnicas · ARAcademia Nacional de Medicina · ARHelios Salud · ARHospital Alemán · ARHospital Ramos Mejía · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Essential thrombocythemia (ET) is comprised among chronic myeloproliferative neoplasms (MPN) and is caused by driver mutations in

Indexed as

AdultAgedBlood PlateletsChemokine CCL5Extracellular Signal-Regulated MAP KinasesFemaleHumansInflammationMaleMiddle AgedNeutrophilsPhosphorylationPlatelet ActivationThrombocythemia, EssentialThrombosisToll-Like ReceptorsCCL5 protein, humanChemokine CCL5Extracellular Signal-Regulated MAP KinasesToll-Like Receptorsessential thrombocythemiainflammationJAK2platelet immunologythrombosistoll-like receptors

Identifiers

PMID32425934
PMCPMC7203216
OpenAlexW3022595966

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.