Evidence map›Paper›PMID 32425777›Full record

ArticleFrontiers in pharmacology2020

Yizhi Qingxin Formula Extract Ameliorates Cognitive Decline in Aged Rats

Lina Ma, Yu Cao, Feixue Wang, Zehui Li, Zhiyong Wang, Yang Yang, Hui Pei, Hao Li

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Lina MaGeriatric Department, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Yu CaoGeriatric Department, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Feixue WangGeriatric Department, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Zehui LiGeriatric Department, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Zhiyong WangGeriatric Department, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Yang YangGeriatric Department, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Hui PeiGeriatric Department, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Hao LiGeriatric Department, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Xiyuan Hospital · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cognitive impairment and decline in old age are primarily driven by the accumulation of age-related neuropathologies, and old age is thus the primary risk factor for neurodegenerative diseases such as AD. Here, we investigated the effects of Yizhi Qingxin formula (YQF) extract on cognitive impairment in aged rats and determine the role of the brain-derived neurotrophic factor (BDNF)/t

Indexed as

aged ratsAlzheimer’s diseasebrain-derived neurotrophic factorcognitive impairmenttropomyosin receptor kinase BYizhi Qingxin formula

Identifiers

PMID32425777
PMCPMC7203446
OpenAlexW3022016967

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.