Evidence map›Paper›PMID 32425663›Full record

ReviewJournal of clinical virology : the official publication of the Pan American Society for Clinical Virology2020

Evidence and possible mechanisms of rare maternal-fetal transmission of SARS-CoV-2.

Charles Egloff, Christelle Vauloup-Fellous, Olivier Picone, Laurent Mandelbrot, Pierre Roques

Open access · greenAbstract readReview
In one paragraph

Review in Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 9 pooled it
11.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 9 syntheses or guidelines pooled it, 125 citations in OpenAlex.

  1. Pooled it
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  4. POTENTIAL RISK OF BRAIN DAMAGE AND POOR DEVELOPMENTAL OUTCOMES IN CHILDREN PRENATALLY EXPOSED TO SARS-COV-2: A SYSTEMATIC REVIEW.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2021
    Pooled it
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  16. The impact of covid-19 pandemic on pregnancy outcome.BMC pregnancy and childbirth · 2023
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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Charles EgloffService de gynécologie-obstétrique, Hôpital Louis Mourier, AP-HP, Université de PARIS, IAME INSERM U1137, Paris, France; IDMIT, CEA, IMVA INSERM U1184, Université Paris Saclay, Fontenay aux Roses, France. Electronic address: charles.egloff@cea.fr.
Christelle Vauloup-FellousService de Virologie, Hôpital Paul Brousse, AP-HP, Inserm U 1193, Université Paris Saclay, Villejuif, France.
Olivier PiconeService de gynécologie-obstétrique, Hôpital Louis Mourier, AP-HP, Université de PARIS, IAME INSERM U1137, Paris, France.
Laurent MandelbrotService de gynécologie-obstétrique, Hôpital Louis Mourier, AP-HP, Université de PARIS, IAME INSERM U1137, Paris, France.
Pierre RoquesIDMIT, CEA, IMVA INSERM U1184, Université Paris Saclay, Fontenay aux Roses, France. Electronic address: pierre.roques@cea.fr.
Inserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While SARS-CoV-2 infection has spread rapidly worldwide, data remains scarce about the natural history of infection in pregnant women and the risk of mother-to-fetal transmission. Current data indicates that viral RNA levels in maternal blood are low and there is no evidence of placental infection with SARS-CoV-2. Published reports to date suggest that perinatal transmission of SARSCoV- 2 can occur but is rare. Among 179 newborns tested for SARS-CoV2 at birth from mothers with COVID-19, transmission was suspected in 8 cases, 5 with positive nasopharyngeal SARS-CoV-2 RT-PCR and 3 with SARS-CoV-2 IgM. However, these cases arise from maternal infection close to childbirth and there are no information about exposition during first or second trimester of pregnancy. Welldesigned prospective cohort studies with rigorous judgement criteria are needed to determine the incidence and risk factors for perinatal transmission of SARS-CoV-2.

Indexed as

Infectious Disease Transmission, VerticalBetacoronavirusCohort StudiesCoronavirus InfectionsCOVID-19FemaleHumansIncidenceInfant, NewbornMothersNasopharynxPandemicsPneumonia, ViralPregnancyProspective StudiesRisk FactorsCellular tropismCOVID-19FetusMaternal-infant infectionNewbornSevere acute respiratory syndromeTrans-placental passage

Identifiers

PMID32425663
PMCPMC7233246
OpenAlexW3025217820

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.