Evidence map›Paper›PMID 32425661›Full record

ArticleJournal of clinical virology : the official publication of the Pan American Society for Clinical Virology2020

Utilizing tocilizumab for the treatment of cytokine release syndrome in COVID-19.

Ali Hassoun, Elizabeth Dilip Thottacherry, Justin Muklewicz, Qurrat-Ul-Ain Aziz, Jonathan Edwards

Abstract readLetterComment
In one paragraph

Article in Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
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  9. Article
  10. Observational
  11. Article
  12. Circulating Calprotectin as a Biomarker of COVID-19 Severity.Expert review of clinical immunology · 2021
    Review
  13. Review
  14. Article
  15. Challenges of Cellular Therapy During the COVID-19 Pandemic.Advances in experimental medicine and biology · 2021
    Article
  16. Review
  17. Article
  18. The role of Interleukin 6 inhibitors in therapy of severe COVID-19.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2020
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Ali HassounClinical Associate Professor in Infectious Diseases, Department of Internal Medicine, Alabama Infectious Diseases Center, 420 Lowell Drive Suite 301, Huntsville, AL, 35801, USA. Electronic address: ali_hasoun@yahoo.com.
Elizabeth Dilip ThottacherryDepartment of Internal Medicine, University of Alabama at Birmingham, School of Medicine - Huntsville Regional Medical Campus, 301 Governor's Drive, Huntsville, AL, 35801, USA. Electronic address: lisa.thottacherry@gmail.com.
Justin MuklewiczHuntsville Hospital Department of Pharmacy, Huntsville Hospital Health Systems, 101 Sively Rd SW, Huntsville, AL, 35801, USA. Electronic address: justin.muklewicz@hhsys.org.
Qurrat-Ul-Ain AzizDepartment of Internal Medicine, University of Alabama at Birmingham, School of Medicine - Huntsville Regional Medical Campus, 301 Governor's Drive, Huntsville, AL, 35801, USA. Electronic address: qaziz04@gmail.com.
Jonathan EdwardsHuntsville Hospital Department of Pharmacy, Huntsville Hospital Health Systems, 101 Sively Rd SW, Huntsville, AL, 35801, USA. Electronic address: jonathan.edwards@hhsys.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BetacoronavirusCytokine Release SyndromeAntibodies, Monoclonal, HumanizedCoronavirus InfectionsCOVID-19HumansPandemicsPneumonia, ViralSARS-CoV-2Antibodies, Monoclonal, Humanizedtocilizumab

Identifiers

PMID32425661
PMCPMC7229471

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.