Evidence map›Paper›PMID 32425636›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2020

Factors associated with the duration of viral shedding in adults with COVID-19 outside of Wuhan, China: a retrospective cohort study.

Lin Qi, Yong Yang, Dixuan Jiang, Chao Tu, Lu Wan, Xiangyu Chen, Zhihong Li

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed, 4 pooled it
4.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 4 syntheses or guidelines pooled it, 173 citations in OpenAlex.

  1. Pooled it
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  5. Exploring the Relationship Between Comorbidities and Prolonged Viral Shedding in COVID-19: A Cycle Threshold Value-Based Investigation.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
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  14. Timing and Predictors of Loss of Infectivity Among Healthcare Workers With Mild Primary and Recurrent COVID-19: A Prospective Observational Cohort Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
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  19. Effects of dexamethasone use on viral clearance among patients with COVID-19: a multicenter cohort study.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2023
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27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Lin QiDepartment of Orthopedics, The Second Xiangya Hospital, Central South University, Changsha 410011, China; Hunan Key Laboratory of Tumor Models and Individualized Medicine, The Second Xiangya Hospital, Changsha 410011, China.
Yong YangIntensive Care Unit, Changsha Central Hospital, University of South China, Changsha 410004, China.
Dixuan JiangDepartment of Respiratory Medicine, The First Hospital of Changsha City, Changsha 410005, China.
Chao TuDepartment of Orthopedics, The Second Xiangya Hospital, Central South University, Changsha 410011, China; Hunan Key Laboratory of Tumor Models and Individualized Medicine, The Second Xiangya Hospital, Changsha 410011, China.
Lu WanDepartment of Orthopedics, The Second Xiangya Hospital, Central South University, Changsha 410011, China; Hunan Key Laboratory of Tumor Models and Individualized Medicine, The Second Xiangya Hospital, Changsha 410011, China; Vaccine and Immunotherapy Center, Infectious Diseases Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, US.
Xiangyu ChenDepartment of Radiology, The Second Xiangya Hospital, Central South University, 139 Renmin Road, Changsha 410011, China.
Zhihong LiDepartment of Orthopedics, The Second Xiangya Hospital, Central South University, Changsha 410011, China; Hunan Key Laboratory of Tumor Models and Individualized Medicine, The Second Xiangya Hospital, Changsha 410011, China.
Central South University · CNSecond Xiangya Hospital of Central South University · CNThe First Hospital of Changsha · CNUniversity of South China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate factors associated with the duration of viral shedding in patients with COVID-19, outside of Wuhan.

methodsIn this retrospective cohort study, patients with laboratory-confirmed COVID-19 in Changsha, China were included. Clinical characteristics, laboratory findings, treatment, and outcome were retrieved. Univariate and multivariate analyses were performed to explore potential factors.

resultsOverall, 147 patients with COVID-19 were included. The median duration of viral shedding (the number of days from symptoms onset until the successive negative detection of SARS-CoV-2 RNA) was 17 days (interquartile range [IQR], 12-21). Multivariate Logistic regression analysis indicated that the highest temperature at admission (odds ratio [OR], 5.200; 95% confidence interval [CI]: 1.190-22.726; p = 0.028), time from symptom onset to admission (OR, 1.740; 95% CI: 1.296-2.337; p < 0.001) and hospital length of stay (OR, 1.604; 95% CI: 1.262-2.040; p < 0.001) were risk factors for prolonged duration of viral shedding.

conclusionsThis study, with a relatively large sample size, focused on the duration of viral shedding and related factors in patients with COVID-19, outside of Wuhan, China. Potential risk factors were identified and should be taken into consideration for the strategy of quarantining infected patients.

Indexed as

Virus SheddingAdultAgedAged, 80 and overBetacoronavirusBody TemperatureChinaCoronavirus InfectionsCOVID-19FemaleHospitalizationHumansLength of StayMaleMiddle AgedMultivariate Analysis2019 novel coronavirus disease (COVID-19)ChangshaRisk factorViral shedding

Identifiers

PMID32425636
PMCPMC7231495
OpenAlexW3024220416

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.