Evidence map›Paper›PMID 32425587›Full record

ArticleJournal of pain research2020

Sex and Gender are Not the Same: Why Identity Is Important for People Living with HIV and Chronic Pain.

Larissa J Strath, Robert E Sorge, Michael A Owens, Cesar E Gonzalez, Jennifer I Okunbor, Dyan M White, Jessica S Merlin, Burel R Goodin

Abstract read
In one paragraph

Article in Journal of pain research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Pain mechanisms in the transgender individual: a review.Frontiers in pain research (Lausanne, Switzerland) · 2024
    Review
  10. Psychological/behavioral interventions for emerging adults with chronic pain.Frontiers in pain research (Lausanne, Switzerland) · 2024
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Occupation as a gendered-role and outcome in systemic sclerosis.Journal of scleroderma and related disorders · 2023
    Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Larissa J StrathUniversity of Alabama at Birmingham, Department of Psychology, Birmingham, AL, USA.ORCID 0000-0002-9616-0177
Robert E SorgeUniversity of Alabama at Birmingham, Department of Psychology, Birmingham, AL, USA.ORCID 0000-0003-4989-9697
Michael A OwensUniversity of Alabama at Birmingham, Department of Psychology, Birmingham, AL, USA.
Cesar E GonzalezUniversity of Alabama at Birmingham, Department of Psychology, Birmingham, AL, USA.
Jennifer I OkunborUniversity of Alabama at Birmingham, Department of Psychology, Birmingham, AL, USA.
Dyan M WhiteUniversity of Alabama at Birmingham, Department of Psychology, Birmingham, AL, USA.
Jessica S MerlinUniversity of Pittsburgh, Department of Medicine, Divisions of General Internal Medicine and Infectious Diseases, Pittsburgh, PA, USA.
Burel R GoodinUniversity of Alabama at Birmingham, Department of Psychology, Birmingham, AL, USA.ORCID 0000-0002-8159-1310

Funding

Virology CoreP30AI027767 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Latesha Ellen Elopre · 1988 to 2026
$84.1M
The Impact of Insomnia on Pain, Physical Function, and Inflammation in HIVR01HL147603 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GOODIN, BUREL R., SORGE, ROBERT · 2019 to 2022
$2.8M
NHLBI NIH HHS R01 HL147603NIAID NIH HHS P30 AI027767
6 · The paper itself

Abstract

backgroundSex differences in pain sensitivity have been well documented, such that women often report greater sensitivity than men. However, clinical reports highlighting sex differences often equate gender and sex. This is a particularly critical oversight for those whose gender identity is different than their genetic sex.

methodsThis preliminary study sets to analyze differences in pain responses between cisgender and transgender individuals living with HIV and chronic pain. A total of 51 African-American participants (24 cisgender men, 20 cisgender women, 7 transgender women) with similar socioeconomic status were recruited. Genetic sex, gender identity, depression and anxiety, pain severity, pain interference and pain-related stigma were recorded. Participants also completed a quantitative sensory testing battery to assess pain in response to noxious heat and mechanical stimuli.

resultsTransgender women and cisgender women demonstrated a greater magnitude of temporal summation for heat pain stimuli or mechanical stimuli compared to cisgender men. Specifically, transgender women reported greater mechanical summation than either cisgender women or cisgender men. Transgender women and cisgender women similarly reported greater chronic pain severity compared to cisgender men.

conclusionThese data support the notion that gender identity may play a more significant role in pain sensation than genetic sex. These results further maintain that not only gender identity and genetic sex are distinct variables but that treatment should be based on identity as opposed to genetic sex.

Indexed as

gender identitypainquantitative sensory testingsex differencestransgender

Identifiers

PMID32425587
PMCPMC7187934

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.