ArticleNeuropsychiatric disease and treatment2020
Similar and Different Regional Homogeneity Changes Between Bipolar Disorder and Unipolar Depression: A Resting-State fMRI Study.
Article in Neuropsychiatric disease and treatment, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Insula activity in resting-state differentiates bipolar from unipolar depression: a systematic review and meta-analysis.Scientific reports · 2021Pooled it
- Neural Effects of Low-Frequency Acupoint Electrical Stimulation Therapy on Patients With Poststroke Motor Dysfunction: A Resting-State Functional Magnetic Resonance Imaging Study.Archives of rehabilitation research and clinical translation · 2026Article
- Differences in the Efficacy of Cognitive Function Treatment Related to Functional Patterns in the Frontal-Limbic Network in Patients With Bipolar Disorder.CNS neuroscience & therapeutics · 2026Article
- The application of amplitude of low-frequency fluctuations metrics in the diagnosis and prediction of treatment response as well as their associated genes and biological processes in patients with bipolar disorder.Translational psychiatry · 2025Article
- Long-term risk of late-life depression in widowed elderly: a five-year follow-up study.BMC geriatrics · 2025Article
- Regional brain function study in patients with primary Sjögren's syndrome.Arthritis research & therapy · 2025Article
- Neuroimaging Changes in the Sensorimotor Network and Visual Network in Bipolar Disorder and Their Relationship with Genetic Characteristics.Biomedicines · 2025Article
- Optimizing multi-domain hematologic biomarkers and clinical features for the differential diagnosis of unipolar depression and bipolar depression.Npj mental health research · 2023Article
- Regional homogeneity alterations in multifrequency bands in patients with extracranial multi-organ tuberculosis: a prospective cross-sectional study.Quantitative imaging in medicine and surgery · 2023Article
- Distinguishing functional and structural MRI abnormalities between bipolar and unipolar depression.Frontiers in psychiatry · 2023Article
- The Instant and Sustained Effect of Electroacupuncture in Postgraduate Students with Depression: An fMRI Study.Neuropsychiatric disease and treatment · 2021Article
- Regional Homogeneity Abnormalities and Its Correlation With Impulsivity in Male Abstinent Methamphetamine Dependent Individuals.Frontiers in molecular neuroscience · 2021Article
- Surface-Based Spontaneous Oscillation in Schizophrenia: A Resting-State Functional Magnetic Resonance Imaging Study.Frontiers in human neuroscience · 2021Article
- Cell-Type-Specific Gene Modules Related to the Regional Homogeneity of Spontaneous Brain Activity and Their Associations With Common Brain Disorders.Frontiers in neuroscience · 2021Article
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8 authors.
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Abstract
objectiveTo investigate the regional homogeneity (ReHo) between unipolar depression (UD) and bipolar disorder (BD), and to search for brain imaging markers for distinguishing UD and BD.
methodsA total of 58 patients who met the diagnosis criteria of UD in DSM-Ⅳ, 40 patients who met the diagnosis criteria of BD in DSM-Ⅳ and 54 healthy controls (HC) completed the resting-state functional magnetic resonance (rs-fMRI) scans. The ReHo of the three groups was compared and Pearson correlation analysis was performed between the ReHo values and the clinical symptoms.
results(1) Significant differences were found in the right hippocampus, right parahippocampal gyrus, right Inferior orbitofrontal gyrus, right superior temporal gyrus, right inferior temporal gyrus, and right middle occipital gyrus across the three groups. (2) Compared to HC, the ReHo in the right parahippocampal gyrus in UD significantly increased. (3) When compared to HC, the ReHo in the right hippocampus in BD significantly increased. The ReHo in the right middle occipital gyrus decreased. (4) Compared to UD, BD exhibited significantly decreased ReHo in the right inferior temporal gyrus. No correlations were observed between the scores of 24-item Hamilton Depression Rating Scale (HDMD-24), Hamilton Anxiety Scale (HAMA), Young Mania Rating Scale (YMRS), and the ReHo values of altered brain regions between BD and UD.
conclusionThe results suggest that there was a considerable difference in the ReHo of brain among UD, BD, and HCs. ReHo in the right inferior temporal gyrus showed significant differences between BD and UD that might serve as neuroimaging markers to identify BD and UD.
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