Evidence map›Paper›PMID 32425523›Full record

ArticleInternational journal of nanomedicine2020

The Pimpled Gold Nanosphere: A Superior Candidate for Plasmonic Photothermal Therapy.

Behzad Nasseri, Mustafa Turk, Kemal Kosemehmetoglu, Murat Kaya, Erhan Piskin, Navid Rabiee, Thomas J Webster

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
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  9. Review
  10. The Biology and Function of Extracellular Vesicles in Cancer Development.Frontiers in cell and developmental biology · 2021
    Review
  11. Review
  12. Photothermal conversion of SiORSC advances · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Behzad NasseriChemical Engineering Department, Bioengineering Division and Bioengineering Centre, Hacettepe University, Ankara 06800, Turkey.
Mustafa TurkBioengineering Department, Kirikkale University, Kirikkale, Turkey.
Kemal KosemehmetogluDepartment of Pathology, Hacettepe Medical Science University, Ankara, Turkey.
Murat KayaChemical Engineering and Applied Chemistry Department, Atilim University, Ankara 06830, Turkey.
Erhan PiskinChemical Engineering Department, Bioengineering Division and Bioengineering Centre, Hacettepe University, Ankara 06800, Turkey.
Navid RabieeDepartment of Chemistry, Shahid Beheshti University, Tehran, Iran.ORCID 0000-0002-6945-8541
Thomas J WebsterDepartment of Chemical Engineering, Northeastern University, Boston, MA 02115, USA.ORCID 0000-0002-2028-5969
Atilim University · TRHacettepe University · TRKırıkkale University · TRNortheastern University · USShahid Beheshti University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe development of highly efficient nanoparticles to convert light to heat for anti-cancer applications is quite a challenging field of research.

methodsIn this study, we synthesized unique pimpled gold nanospheres (PGNSs) for plasmonic photothermal therapy (PPTT). The light-to-heat conversion capability of PGNSs and PPTT damage at the cellular level were investigated using a tissue phantom model. The ability of PGNSs to induce robust cellular damage was studied during cytotoxicity tests on colorectal adenocarcinoma (DLD-1) and fibroblast cell lines. Further, a numerical model of plasmonic (COMSOL Multiphysics) properties was used with the PPTT experimental assays.

resultsA low cytotoxic effect of thiolated polyethylene glycol (SH-PEG

conclusionCollectively, such results show much promise for the use of the present PGNSs and photothermal therapy for numerous anti-cancer applications.

Indexed as

AdenocarcinomaApoptosisCell Line, TumorCell SurvivalColorectal NeoplasmsFibroblastsGoldHumansLasersNanospheresNeoplasmsPhantoms, ImagingPhototherapyPolyethylene GlycolsGoldpolyethylene glycol 400Polyethylene Glycolscolorectal cellsgold nanoparticlespathologyphotothermal therapyplasmonic

Identifiers

PMID32425523
PMCPMC7188077
OpenAlexW3018785667

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.