Evidence map›Paper›PMID 32425482›Full record

ArticleJSLS : Journal of the Society of Laparoendoscopic Surgeons

Gall Bladder Empyema: Early Cholecystectomy during the Index Admission Improves Outcomes.

Hisham El Zanati, Ahmad H M Nassar, Samer Zino, Tarek Katbeh, Hwei Jene Ng, Ayman Abdellatif

Registry-linked trialAbstract read
In one paragraph

Article in JSLS : Journal of the Society of Laparoendoscopic Surgeons. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04405713 (Assessment of Different Timing for Early Laparoscopic Cholecystectomy in Acute Calcular Cholecystitis), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04405713 nacompletednot on this map

Assessment of Different Timing for Early Laparoscopic Cholecystectomy in Acute Calcular Cholecystitis (Multicentric Study)

TypeinterventionalSponsorMansoura UniversityRan2018 to 2020Enrolled900ConditionsAcute CholecystitisArmsfrom the onset of symptoms within the first 3 days, : from the onset of symptoms within the 4-7 days, from the onset of symptoms beyond 7 days
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hisham El ZanatiDepartment of General Surgery, University Hospital Monklands, Airdrie, Lanarkshire, United Kingdom.
Ahmad H M NassarDepartment of General Surgery, University Hospital Monklands, Airdrie, Lanarkshire, United Kingdom.
Samer ZinoDepartment of General Surgery, University Hospital Monklands, Airdrie, Lanarkshire, United Kingdom.
Tarek KatbehDepartment of General Surgery, University Hospital Monklands, Airdrie, Lanarkshire, United Kingdom.
Hwei Jene NgDepartment of General Surgery, University Hospital Monklands, Airdrie, Lanarkshire, United Kingdom.
Ayman AbdellatifDepartment of General Surgery, University Hospital Monklands, Airdrie, Lanarkshire, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWe aim to evaluate our policy of index admission management of gall bladder empyema and the effect of the timing of surgery on the outcomes.

methodsWe analyzed a series of 5400 laparoscopic cholecystectomies. Data were collected prospectively over 26 y. Patients were divided into two groups: group 1, intervention within 72 h, and group 2, intervention after 72 h of admission. We had a policy of intention to treat during the index admission, but delays sometimes occurred because of late referral, a need to optimize patients, availability of theater time, or the biliary surgeon being on leave. The groups were then compared with regard to the duration of surgery, the difficulty grading, complications, hospital stay, and conversion rate.

resultsA total of 372 patients were included; 160 (43%) operated on within 72 h (group 1) and 212 (57%) after 72 h (group 2). There was no statistically significant difference between the two groups with regard to the operation time, conversion rate, and complications rate. The difference in total hospital stay was, however, statistically significant.

conclusionSurgical management of empyema should be offered as soon as possible after admission as with any acute cholecystitis. Surgery carried out after 72 h of admission is only associated with longer hospital stay but no statistically significant differences in other outcome parameters. In the presence of specialist expertise, fitness for surgery should be the determining factor of whether or not to offer surgery to these patients, regardless of the interval since their admission.

Indexed as

Cholecystectomy, LaparoscopicPatient AdmissionTime-to-TreatmentAdultAgedAged, 80 and overCholecystitisCholecystitis, AcuteFemaleHumansLength of StayMaleMiddle AgedOperative TimeTreatment OutcomeYoung Adultdifficulty gradinggallbladder empyemaintraopertative cholangiographylaparoscopic cholecystectomyNassar scale

Identifiers

PMID32425482
PMCPMC7208918

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.