Evidence map›Paper›PMID 32425376›Full record

ArticleIndian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion2020

"Hairy Cell Leukemia (HCL): 'Real World' Outcome".

Archit Joshi, Manikandan Dhanushkodi, Prasanth Ganesan, Venkatraman Radhakrishnan, Krishnarathinam Kannan, Nikita Mehra, Jayachandran Perumal Kalaiyarasi, S Krupashankar, Shirley Sundersingh, T S Ganesan and 1 more

Abstract read
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Article in Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Archit Joshi1Department of Medical Oncology, Cancer Institute (WIA), Chennai, Tamil Nadu 600036 India.
Manikandan Dhanushkodi1Department of Medical Oncology, Cancer Institute (WIA), Chennai, Tamil Nadu 600036 India.ORCID 0000-0002-8192-3856
Prasanth Ganesan1Department of Medical Oncology, Cancer Institute (WIA), Chennai, Tamil Nadu 600036 India.
Venkatraman Radhakrishnan1Department of Medical Oncology, Cancer Institute (WIA), Chennai, Tamil Nadu 600036 India.
Krishnarathinam Kannan1Department of Medical Oncology, Cancer Institute (WIA), Chennai, Tamil Nadu 600036 India.
Nikita Mehra1Department of Medical Oncology, Cancer Institute (WIA), Chennai, Tamil Nadu 600036 India.
Jayachandran Perumal Kalaiyarasi1Department of Medical Oncology, Cancer Institute (WIA), Chennai, Tamil Nadu 600036 India.
S Krupashankar1Department of Medical Oncology, Cancer Institute (WIA), Chennai, Tamil Nadu 600036 India.
Shirley Sundersingh2Department of Oncopathology, Cancer Institute (WIA), Chennai, Tamil Nadu 600036 India.
T S Ganesan1Department of Medical Oncology, Cancer Institute (WIA), Chennai, Tamil Nadu 600036 India.
T G Sagar1Department of Medical Oncology, Cancer Institute (WIA), Chennai, Tamil Nadu 600036 India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

HCL is an uncommon B cell lympho-proliferative disorder with high remission rates. There is paucity of data on the long-term outcome of HCL from India. We retrospectively collected data from individual case records of patients with HCL who were treated in Cancer Institute, Chennai from January 2001 until January 2018. Sixteen patients were diagnosed with HCL and were treated with cladribine (81%), interferon (13%) and one patient received only best supportive care (6%). All the treated patients achieved complete response. More than half of the patients developed febrile neutropenia but there were no treatment related mortality. The 5-year DFS was 77% and 5-year OS was 80%. Relapse of disease was seen in 27%. HCL is a curable malignancy with high remission rates and survival comparable to patient treated in west.

Indexed as

Hairy cell leukemiaOutcomeSurvival

Identifiers

PMID32425376
PMCPMC7229049

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.