ReviewThe American journal of emergency medicine2020
Neurologic complications of COVID-19.
Review in The American journal of emergency medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04429477 (Assessment of Cerebral Compliance and Hemodynamics in Severe COVID-19), which is not on this map. Cited by 115 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Assessment of Cerebral Compliance and Hemodynamics in Severe COVID-19
Who cites it
115 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) following COVID-19 vaccines: A systematic review.Revue neurologique · 2023Pooled it
- Neurological manifestations in patients with COVID-19: A systematic review and meta-analysis.Journal of clinical laboratory analysis · 2022Pooled it
- COVID-19, Anti-NMDA Receptor Encephalitis and MicroRNA.Frontiers in immunology · 2022Pooled it
- Treatment Options for COVID-19-Related Guillain-Barré Syndrome: A Systematic Review of Literature.The neurologist · 2021Pooled it
- Prognostic value of apolipoproteins in COVID-19 patients: A systematic review and meta-analysis.Travel medicine and infectious diseasePooled it
- A nomogram model for early recognition of acute necrotizing encephalopathy: a retrospective study.Translational pediatrics · 2026Article
- Article
- Significance of Neurological Manifestations and Their Association With Clinical Outcomes in Hospitalized COVID-19 Patients in Bandar Abbas, Iran: A Cross-Sectional Study.Health science reports · 2025Article
- Clinical Characteristics of COVID-19-Related Reversible Cerebral Vasoconstriction Syndrome: A Systematic Review of Case Series.Journal of clinical medicine · 2025Review
- A cross-sectional study on the long-term impact of COVID-19: Symptoms, disability and daily functioning.Health SA = SA Gesondheid · 2025Article
- Lithium in the time of COVID: forever vigilant.International journal of bipolar disorders · 2024Article
- Recurrent COVID-19-related psychotic disorder with neuro-immuno-endocrine dysfunction as a possible underlying mechanism: A case report from China.Brain, behavior, & immunity - health · 2024Article
- Article
- A Case of Intractable Hypophosphatemia in a Patient with Guillain-Barré Syndrome and Encephalitis after SARS-CoV-2 Infection.Endocrine, metabolic & immune disorders drug targets · 2024Article
- COVID-19 increases a person's risk of cardiovascular problems: how common is chronic heart failure in SARS-CoV-2 patients? a case report.Annals of medicine and surgery (2012) · 2023Article
- Update on the effectiveness of COVID-19 vaccines on different variants of SARS-CoV-2.International immunopharmacology · 2023Review
- Article
- Cognitive function in recovered COVID-19 Lebanese patients with schizophrenia.Annals of general psychiatry · 2023Article
- Article
- Can Patients with Asymptomatic/Mild Illness and Moderate Illness COVID-19 Have White Matter Damage?International journal of general medicine · 2023Article
55 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMuch of the focus regarding the global pandemic of coronavirus disease of 2019 (COVID-19) has been on the cardiovascular, pulmonary, and hematologic complications. However, neurologic complications have arisen as an increasingly recognized area of morbidity and mortality.
objectiveThis brief report summarizes the neurologic complications associated with COVID-19 with an emphasis on the emergency medicine clinician. DISCUSSION: COVID-19 has infected over 3.5 million people and killed over 240,000 people worldwide. While pulmonary complications are profound, the neurologic system is also significantly impacted, with complications including acute cerebrovascular events, encephalitis, Guillain-Barré syndrome, acute necrotizing hemorrhagic encephalopathy, and hemophagocytic lymphohistiocytosis. Additionally, patients on immunosuppressive medications for pre-existing neurologic issues are at an increased risk for complications with COVID-19 infection, and many of the currently proposed COVID-19 therapies can interact with these medications.
conclusionsWhen caring for COVID-19 patients, emergency medicine clinicians should be aware of the neurologic complications from COVID-19.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.