ReviewTherapeutic advances in respiratory disease
Contemporary best practice in the management of pulmonary embolism during pregnancy.
Review in Therapeutic advances in respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Pulmonary embolism consensus.Archivos de cardiologia de Mexico · 2026Article
- Postpartum Venous Thromboembolism: Altitudinal Gradients, Decadal Trends, and PE-Specific Risk Profiling in Highland Populations.Canadian respiratory journal · 2026Article
- The Knowledge, Attitude, and Practice Regarding Deep Vein Thrombosis Among Pregnant and Postpartum Women: The Mediating Effect of Attitude.Nursing open · 2025Article
- Diagnosing Pulmonary Embolism During Pregnancy.Chest · 2025Review
- Evaluating Thromboprophylaxis Strategies for High-Risk Pregnancy: A Current Perspective.Pharmaceuticals (Basel, Switzerland) · 2024Review
- Predictors of thrombosis during VV ECMO: an analysis of 9809 patients from the ELSO registry.Journal of thrombosis and thrombolysis · 2024Article
- Article
- Risk factors, diagnosis and management of venous thromboembolic disease in pregnancy.Breathe (Sheffield, England) · 2022Review
- Inter-Specialty Controversies on the Treatment of Cardiovascular Diseases during Pregnancy: A Questionnaire Study.Medicina (Kaunas, Lithuania) · 2022Article
- Postpartum prophylaxis of venous thromboembolism with anticoagulation: A case report.Journal of Taibah University Medical Sciences · 2021Article
- Diagnostic imaging to investigate pulmonary embolism in pregnancy using CT-Pulmonary angiography versus perfusion scan.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2021Article
- Anticoagulation for COVID-19 Patients: A Bird's-Eye View.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisReview
- Fondaparinux Pre-, Peri-, and/or Postpartum for the Prophylaxis/Treatment of Venous Thromboembolism (FondaPPP).Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Approximately 1-2 per 1000 pregnancies are complicated by venous thromboembolism (VTE). VTE includes deep vein thrombosis (DVT) and pulmonary embolism (PE) and the diagnostic management of pregnancy-related VTE is challenging. Current guidelines vary greatly in their approach to diagnosing PE in pregnancy as they base their recommendations on scarce and weak evidence. The pregnancy-adapted YEARS diagnostic algorithm is well tolerated and is the most efficient diagnostic algorithm for pregnant women with suspected PE, with 39% of women not requiring computed tomographic pulmonary angiography. Low-molecular-weight heparin is the first-choice anticoagulant treatment in pregnancy and should be continued until 6 weeks postpartum and for a minimum of 3 months. Direct oral anticoagulants should be avoided in women who want to breastfeed. Management of delivery needs a multidisciplinary approach in order to decide on an optimal delivery plan. Neuraxial analgesia can be given in most patients, provided time windows since last low-molecular-weight heparin dose are respected. Women with a history of VTE are at risk of recurrence during pregnancy and in the postpartum period. Therefore, in most women with a history of VTE, thromboprophylaxis in subsequent pregnancies is indicated.
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