Evidence map›Paper›PMID 32424966›Full record

ArticleJournal of cellular and molecular medicine2020

p75NTR optimizes the osteogenic potential of human periodontal ligament stem cells by up-regulating α1 integrin expression.

Jun Li, Manzhu Zhao, Yingying Wang, Mengjie Shen, Shuai Wang, Mengying Tang, Meng Li, Yuting Luo, Kun Yang, Xiujie Wen

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  4. Article
  5. Article
  6. Research progress of dental pulp regeneration treatment.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024
    Review
  7. Role of the GRP78-c-Src signaling pathway on osteoblast differentiation of periodontal ligament fibroblasts induced by cyclic mechanical stretch.Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2024
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Jun LiDepartment of Stomatology, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, China.ORCID 0000-0001-7155-8376
Manzhu ZhaoCollege of Stomatology, Chongqing Medical University, Chongqing, China.
Yingying WangDepartment of Stomatology, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Mengjie ShenHospital of Stomatology, Zunyi Medical University, Zunyi, China.
Shuai WangHospital of Stomatology, Zunyi Medical University, Zunyi, China.
Mengying TangHospital of Stomatology, Southwest Medical University, Luzhou, China.
Meng LiCollege of Stomatology, Chongqing Medical University, Chongqing, China.
Yuting LuoCollege of Stomatology, Chongqing Medical University, Chongqing, China.
Kun YangHospital of Stomatology, Zunyi Medical University, Zunyi, China.ORCID 0000-0002-7720-8681
Xiujie WenDepartment of Stomatology, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, China.ORCID 0000-0003-1308-6790
Army Medical University · CNStomatological Hospital of Chongqing Medical University · CNZunyi Medical University · CNSouthwest Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human periodontal ligament stem cells (hPDLSCs) are a promising source in regenerative medicine. Due to the complexity and heterogeneity of hPDLSCs, it is critical to isolate homogeneous hPDLSCs with high regenerative potential. In this study, p75 neurotrophin receptor (p75NTR) was used to isolate p75NTR

Indexed as

OsteogenesisUp-RegulationAdolescentAdultBiomarkersCell DifferentiationGene SilencingHumansIntegrin alpha1Periodontal LigamentReceptor, Nerve Growth FactorStem CellsYoung AdultBiomarkersIntegrin alpha1Receptor, Nerve Growth Factorcell surface markerhuman periodontal ligament stem cellsosteogenic differentiationregenerative medicinesignalling pathway

Identifiers

PMID32424966
PMCPMC7339167
OpenAlexW3024198877

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.