Evidence map›Paper›PMID 32424800›Full record

ArticleLung2020

The Significance of Controlling Nutritional Status (CONUT) Score as a Novel Prognostic Parameter in Small Cell Lung Cancer.

Ali Yılmaz, Salim Başol Tekin, Mehmet Bilici, Hatice Yılmaz

Abstract read
PubMed Publisher
In one paragraph

Article in Lung, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 5 pooled it
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 5 syntheses or guidelines pooled it, 49 citations in OpenAlex.

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  18. Silently Proliferating: Cancer.The Eurasian journal of medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ali YılmazDepartment of Medical Oncology, Atatürk University Faculty of Medicine, Erzurum, 25100, Turkey. draliyilmaz-h@hotmail.com.ORCID 0000-0001-6078-8651
Salim Başol TekinDepartment of Medical Oncology, Atatürk University Faculty of Medicine, Erzurum, 25100, Turkey.
Mehmet BiliciDepartment of Medical Oncology, Atatürk University Faculty of Medicine, Erzurum, 25100, Turkey.
Hatice YılmazDepartment Of Medical Oncology, Adnan Menderes University Faculty of Medicine, Aydın, Turkey.
Atatürk University · TRAdnan Menderes University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe immuno-nutritional status is closely related to the prognosis in many cancers. Controlling nutritional status (CONUT) score is a new parameter that reflects the immuno-nutritional status and is prognostic in some cancers. However, the prognostic significance of the CONUT score in small cell lung cancer (SCLC) is unknown. We aimed to demonstrate the prognostic significance of the CONUT score in patients with SCLC.

methodsTwo hundred sixteen patients who were followed up with SCLC were included in the study retrospectively. According to the receiver operating characteristic (ROC) curve analysis, the optimal cutoff values were determined for the CONUT score, and the patients were divided into low (< 2) and high (≥ 2) CONUT groups. Neutrophil-lymphocyte ratio (NLR), systemic immune-inflammation index (SII), and prognostic nutritional index (PNI) were grouped based on a cutoff point 2.84, 626, and 46.1, respectively. Cox regression analyses were used to assess their prognostic values for progression-free survival (PFS) and overall survival (OS).

resultsThe high CONUT group had significantly worse PFS and OS than the low CONUT group (p < 0.001, p < 0.001). In univariate analysis, stage, prophylactic cranial irradiation, extrapulmonary lesion, PNI, body mass index, CONUT score were found to be significant for both PFS and OS. In multivariate analysis, only CONUT score and stage were found as independent prognostic factors for both PFS (p: 0.018, p: 0.046) and OS (p: 0.038, p: 0.006).

conclusionThe CONUT score at the time of diagnosis is an independent prognostic parameter that predicts recurrence and survival times in SCLC.

Indexed as

Body Mass IndexCholesterolFemaleHumansLeukocyte CountLung NeoplasmsLymphocyte CountLymphocytesMaleMiddle AgedNeoplasm StagingNeutrophilsNutritional StatusNutrition AssessmentPrognosisProgression-Free SurvivalCholesterolSerum AlbuminControlling nutritional statusPrognosisSmall cell lung cancerSurvival

Identifiers

PMID32424800
OpenAlexW3028204042

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.